Last updated: June 04, 2012
Chimpanzee Genome Sequencing
In early 2002, the National Human Genome Research Institute (NHGRI) agreed to support a chimpanzee genome sequencing project initially aimed at producing 6- to 8-fold, whole genome shotgun sequence coverage of the chimpanzee (Pan troglodytes) genome. A short time later, in late 2003, a decision was made to support a proposal to complete a high-quality (6- to 8-fold coverage) genome assembly. Paired end reads from plasmids, fosmids, and BACs will be assembled and the assembly will be analyzed before a decision is made to continue sequencing to a greater depth of coverage.
The chimpanzee genome sequencing project is led by the Broad Institute/MIT Center for Genome Research and the Washington University Genome Sequencing Center.
Genome Sequencing Whitepaper Proposal:
- Pan troglodytes
(Submitted Feb. 2002)
- Pan troglodytes
(Submitted Oct. 2002)
Project Link:
- Washington University Genome Sequencing Center [genome.wustl.edu]
Supporting Institutions:
- Broad Institute [broadinstitute.org]
Additional Resources
Sequence and Assembly
- Individual Sequence Reads:
- NCBI Trace Archive [ncbi.nlm.nih.gov]
ESTs
- dbEST [ncbi.nlm.nih.gov]- Database of ESTs at NCBI
SNPs
- dbSNP [ncbi.nlm.nih.gov]- Database of Single Nucleotide Polymorphisms at NCBI
BAC Libraries
- Children's Hospital Oakland Research Institute (CHORI) - Chimpanzee BAC libraries:
- CHORI-251 Chimpanzee BAC library [bacpac.chori.org]
- RPCI - 43 Male Chimpanzee BAC Library [bacpac.chori.org]
- CHORI-1251: Chimpanzee Fosmid Library [bacpac.chori.org]