Rhesus Macaque Genome Sequencing

The National Human Genome Research Institute (NHGRI) currently supports a rhesus macaque genome sequencing project, co-led by the Baylor College of Medicine Genome Sequencing Center, the Washington University Genome Sequencing Center, and the Joint Technologies Center/The Institute for Genome Research (JTC/TIGR), that aims to produce between 5- and 6-fold sequence coverage of the rhesus macaque (Macaca mulatta) genome using a mix of whole genome shotgun sequencing (WGS) and Bacterial Artificial Chromosome (BAC)-based sequencing strategies.

Genome Sequencing Proposal

• Macaca mulatta
  Draft Assembly
  (Submitted Oct. 2002)
   
• Macaca mulatta
  Targeted BAC Finishing
  (Submitted Feb. 2006)

Project Links

• Baylor College of Medicine Genome Sequencing Center [hgsc.bcm.tmc.edu]
• Washington University (St. Louis) Genome Sequencing Center [genome.wustl.edu]

Additional Resources Sequence and Assembly

• Individual Sequence Reads:
  • NCBI Trace Archive [ncbi.nlm.nih.gov]

Mapping

• Bioinformatics Research Laboratory (BRL) Rhesus Project Site [brl.bcm.tmc.edu]
  Provides access to the current comparative physical map of the rhesus macaque genome.

ESTs

• dbEST [ncbi.nlm.nih.gov]- Database of ESTs at NCBI

BAC Libraries

• Children's Hospital Oakland Research Institute (CHORI) - Rhesus Macaque BAC libraries
  • CHORI-250: Rhesus Macaque (M) BAC Library [bacpac.chori.org]