Last updated: May 29, 2014
Future Directions for the eMERGE Network
January 22, 2014
Hyatt Regency Bethesda
7400 Wisconsin Avenue
Bethesda, Md. 20814
On January 22, 2014, the National Human Genome Research Institute (NHGRI) sponsored the eMERGE Network Workshop - Future Directions for the eMERGE Network - at the Hyatt Regency Bethesda in Bethesda, Md. The workshop brought together eMERGE principal investigators (PIs) and workgroup co-chairs, the eMERGE External Scientific Panel (ESP), and external experts in key areas of genomic medicine to review the current goals and accomplishments of eMERGE and suggest future directions for NHGRI to consider as the possibility of an eMERGE Phase III approaches. Dan Masys, M.D., Ph.D., University of Washington, chaired this workshop.
eMERGE Workshop Executive Summary 
| Time | Topic | Presenter/Moderator |
|---|---|---|
| 8:00 - 8:15 a.m. | Welcome, Introductions and Opening Remarks | Eric Green, M.D., Ph.D NHGRI Dan Masys, M.D., Ph.D. (Chair) University of Washington |
| 8:15 - 8:30 a.m. | NHGRI Genomic Medicine Portfolio | Eric Green, M.D., Ph.D NHGRI |
| 8:30 - 9:15 a.m. | eMERGE Program Overview - (PGx, CERC, etc.) | Rex Chisholm, Ph. D. Northwestern University |
| PANEL PRESENTATION AND DISCUSSION | ||
| 9:15 - 10:05 a.m. | Balancing discovery and implementation in eMERGE
Roden: Video | Slides |
eMERGE: Dan Roden, M.D. Vanderbilt University Reaction: Mary Relling, Pharm.D. St. Jude Children's Research Hospital Summary: Howard McCleod, Pharm.D. Moffitt Cancer Center |
| 10:05 - 10:20 a.m. | Break | |
| 10:20 - 11:10 a.m. | EMR and Clinical Phenotyping: Challenges and New Opportunities
Denny: Video | Slides |
eMERGE: Josh Denny, M.D., M.S. Vanderbilt University Reaction: Daniel Masys, M.D. University of Washington Summary: Chris Chute, M.D., Dr. Ph. Mayo Clinic |
| 11:10 a.m. - 12:00 p.m. | EMR and Genomic Discovery - Beyond GWAS, Pharmcogenomics Ritchie: Video | Slides Nickerson: Video | Slides Leeder: Video | Slides |
eMERGE: Marylyn Ritchie, Ph.D. Pennsylvania State University Reaction: Debbie Nickerson, Ph.D. University of Washington Summary: Steve Leeder, Pharm.D., Ph.D. University of Kansas Medical Center |
| 12:00 - 12:30 p.m. | Working Lunch | |
| 12:30 - 1:20 p.m. | Genomic Testing (genotyping/sequencing) - Actionability, Validation and Standards of Lab Reports
Rasmussen-Torvik: Video | Slides |
eMERGE: Laura Rasmussen-Torvik, Ph.D. Northwestern University Reaction: Heidi Rehm, Ph.D. Partners Healthcare Summary: Dick Weinshilboum, M.D. Mayo Clinic |
| 1:20 - 2:10 p.m. | Informed Consent, Education & Governance - ELSI | eMERGE: Maureen Smith, M.S., C.G.C. Northwestern University Reaction: Wendy Chung, M.D., Ph.D. Columbia University Summary: Reed Pyeritz, M.D., Ph.D. University of Pennsylvania |
| 2:10 - 3:00 p.m. | Return of Genomic Results - Current Applications and Challenges Kullo: Video | Slides Meyer: Video | Slides Parker: Video | Slides |
eMERGE: Iftikhar Kullo, M.D. Mayo Clinic Reaction: Laurence Meyer, M.D., Ph.D. Veterans Administration Medical Center Summary: Lisa Parker, Ph.D. University of Pittsburgh |
| 3:00 - 3:20 p.m. | Break | |
| 3:20 - 4:10 p.m. | EMR Integration and Genomic Medicine Implementation - Big Data, Clinical Disseminations, Clinical Validities & Utilities
Williams: Video | Slides |
eMERGE: Marc Williams, M.D. Geisenger Health System Reaction: Eta Berner, Ed.D. University of Alabama at Birmingham Summary: J. Michael Gaziano, M.D., M.P.H. Brigham and Women's Hospital |
| 4:10 - 5:00 p.m. | Genomic Medicine in Pediatric Patients - Obstacles and Future Directions
Hakonarson: Video | Slides |
eMERGE: Hakon Hakonarson, M.D., Ph.D. Children's Hospital of Philadelphia Reaction: Robert Nussbaum, M.D. University of California, San Francisco Summary: Jeff Botkin, M.D., M.P.H. University of Utah |
| 5:00 - 5:30 p.m. | Summary and Recommendations for Future Directions | Dan Masys, M.D., Ph.D. University of Washington Teri Manolio, M.D., Ph.D. NHGRI |
| 5:30 p.m. | Adjourn | |