MAGen NOFO Webinar

NHGRI hosted an application webinar for the ML/AI Tools to Advance Genomic Translational Research (MAGen) notice of funding opportunities (NOFOs): RFA-HG-24-004 and RFA-HG-24-005. The purpose of these NOFOs is to explore the feasibility of developing Machine Learning (ML) and Artificial Intelligence (AI) tools that can enhance the accuracy and precision of predicting how individuals with pathogenic genetic variants manifest disease. The objective is to collaboratively identify both genomic and non-genomic factors influencing disease development in individuals carrying pathogenic genetic variants within a research consortium, ML/AI Tools to Advance Genomic Translational Research (MAGen). The ML/AI tools will leverage existing multimodal genomic and non-genomic data and will be cross validated in genomic translational research settings to ensure the robustness and generalizability of the tools. In addition, the Consortium will explore the ethical, legal, and social implications (ELSI) of integrating ML/AI tools into genomic medicine through the establishment of an ELSI framework for their development and through implementation of ELSI research projects. The resources generated by the Consortium will be disseminated to the research community.