Search Results
Facet (Page)
Refine Your Search
Content Formats
Educational Resources
BRCA1 and BRCA2 are the first two genes found to be associated with inherited forms of breast cancer.
… BRCA1/BRCA2 … BRCA1 and BRCA2 are the first two genes found to be associated with … Genes, DNA Repair, Family Health History … BRCA1 and BRCA2 are the first two genes found to be associated with …
Talking Glossary
BRCA1 y BRCA2 son los dos primeros genes que se identificaron como asociados a tipos hereditarios del cáncer de mama y de ovario. Las personas con mutaciones en BRCA1 o BRCA2 tienen un riesgo mucho más alto de desarrollar cáncer de mama, de ovario u otros tipos de cáncer en comparación con las personas que no tienen mutaciones en estos genes.
… BRCA1/BRCA2 … BRCA1 y BRCA2 son los dos primeros genes que se identificaron como … mama y de ovario. Las personas con mutaciones en BRCA1 o BRCA2 tienen un riesgo mucho más alto de desarrollar cáncer …
Genetic Disorders
Breast cancer is the second most common cancer in women after skin cancer.
… year later, a second gene associated with breast cancer - BRCA2 - was discovered on chromosome 13. When individuals carry a mutated form of either BRCA1 or BRCA2, they have an increased risk of developing breast or … point in their lives. Children of parents with a BRCA1 or BRCA2 mutation have a 50 percent chance of inheriting the …
News Release
NHGRI researchers have identified a genomic signature for some aggressive prostate tumors, which may help healthcare providers pinpoint treatment options.
… the National Cancer Institute . The new finding focuses on BRCA2 mutations, which are associated with breast and ovarian … prostate cancer. Both men and women can inherit a faulty BRCA2 gene from either their mother or father. When working properly, the BRCA2 gene helps stop cells from becoming cancerous by …
Policy Issues
In June 2013, the Supreme Court determined that DNA in its natural form cannot be patented.
… the constitutionality and validity of the BRCA1 and BRCA2 gene patents. Myriad Genetics had been particularly …  and against Myriad Genetics, finding that the BRCA1 and BRCA2 genes were products of nature and therefore not …
Genomics and Medicine
Starting in 2019, the American Journal of Human Genetics has published an annual feature identifying ten key advances in applying genomic information to clinical care that were reported in the previous 12 months of published literature. The Genomic Medicine Working Group has authored these reviews, based on its broader effort to identify notable accomplishments in genomic medicine on a monthly basis. From this larger set of published accomplishments, the working group has continued to select ten papers annually to be highlighted as the most significant.
… with Sudden Death What We’re Missing: Most BRCA1 and BRCA2 Variant Carriers Are Undetected Cascade Screening for …
Staff
Dr. Lawrence Brody is a senior investigator in NHGRI's Social and Behavioral Research Branch and director of NHGRI's Division of Genomics and Society.
​
… was among the first to report that women carrying BRCA1 or BRCA2 mutations have a higher risk of developing both breast … While the laboratory no longer studies BRCA1 and BRCA2 at the bench, Dr. Brody continues to carry out … genetic testing. More than 2,000 distinct BRCA1 and BRCA2 mutations have been identified to date, and have been …
Staff
Dr. Peter McGuire is an investigator in NHGRI's Center for Precision Health Research.
… H., Borgen, P., Brown, K., Skolnick, M., et al. Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected …
Policy Issues
En una decisión histórica en junio de 2013, el Tribunal Supremo determinó que el ADN en su forma natural no puede ser patentado.
… y validez de las patentes génicas de BRCA1 y BRCA2. Myriad Genetics habÃa sido especialmente activa en la … de Myriad Genetics, determinando que los genes BRCA1 y BRCA2 eran productos de la naturaleza y, por ende, no eran …
File
… LMNA RYR2 OTC BMPR1A MAX SCN5A BRCA1 MEN1 SDHAF2 Recessive BRCA2 MET SDHB AT P 7 B CACNA1C MLH1 SDHC BCHE CACNA1S MLH3 …