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A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli).
… Bacterial Artificial Chromosome (BAC) … A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). … Cloning, Bacteria, …
News Release
The skin microbiota plays an intricate role in the human immune system, directing many immune functions and defending against bacterial pathogens.
… functions and helping to defend its host against invading bacterial pathogens. … In a review article in the Nov. 21, 2014, issue … directing many immune functions and defending against bacterial pathogens. … Skin microbiota and the microbiome, …
News Release
Researchers from NHGRI, Oxford University and other National Institutes of Health centers have developed and tested a new method to predict hospital-acquired infections involving five other important pathogens.
… infections involving five other important pathogens. Your browser does not support the video tag. … patient suspected of infection with one of the five pathogens we studied,” said Laura Koehly, Ph.D., chief of the … the data, the team could predict subsequent infection for bacterial and viral pathogens that commonly cause …
Staff
Dr. Julie Segre is chief and a senior investigator in the Translational and Functional Genomics Branch at the National Human Genome Research Institute.
… Segre published the first topographical maps of human skin bacterial and fungal diversity. Dr. Segre's laboratory also … the human skin microbiome and tracking hospital-associated bacterial pathogens. It performed the first skin bacterial survey, …
News Release
Researchers at NHGRI have discovered an immune mechanism in humans that perceives threats and was found only in plants.
… human physiology, the innate immune system responds to pathogens, like bacterial toxins, through full-blown fever and a recruitment … in the gene that encodes the pyrin protein, but certain bacterial infections spark the same activation of the pyrin …
Educational Resources
Bacteria are small single-celled organisms.
… full of bacteria, and in fact is estimated to contain more bacterial cells than human cells. Most bacteria in the body …
Research Funding
NHGRI aims to establish a research Consortium, ML/AI Tools to Advance Genomic Translational Research (MAGen), to collaboratively explore the feasibility of Machine Learning (ML) and Artificial Intelligence (AI) tools that can enhance the accuracy and precision of predicting how individuals with pathogenic genetic variants manifest disease.
15 Ways Genomics Influences Our World
Genomics is advancing the study of individual and communities of microbes.
… infections, you can't live without others? Viral and bacterial genomes might be small, but they are packed with … the resistance trait. DNA sequencing of many, many bacterial species has now shown us that there has been … of microbes. … Microbes, Microbiomes, Viral And Bacterial Genomes, Microbial Communities, Antibiotics …
Secondary Genomics Findings Service
How to send data, confirming preliminary results, and returning results
Staff
Dr. Sean Conlan is an associate investigator in the Translational and Functional Genomics Branch at the National Human Genome Research Institute.
… in medical biochemistry from Texas A&M University studying bacterial membrane proteins in the laboratory of Dr. Hagan … Health, where he used motif finding algorithms to identify bacterial regulatory networks. From 2006 to 2008, he developed computational tools for detecting pathogens in clinical samples as part of the Center for …