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- Ethical, Legal and Social Implications (ELSI) Research Program6
- Genomics-Enabled Learning Health Systems (gLHS)2
- Genetic Architecture of Complex Traits1
- Genome Technology Program5
- Human Genome Reference Program (HGRP)2
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Encyclopedia of DNA Elements (ENCODE) Project1
- Molecular Phenotypes of Null Alleles in Cells (MorPhiC)1
- Genomic Innovator Awards2
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)3
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium2
- Developmental Genotype-Tissue Expression (dGTEx)1
- Multi-Omics for Health and Disease (Multi-Omics)1
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… Liaison Branch … In the largest genomics study of clear cell endometrial cancer (CCEC) tumors to date, National Human Genome Research Institute (NHGRI) researchers and their …
Educational Resources
Cancer is a group of diseases characterized by uncontrolled cell growth.
… Cancer … Cancer is a group of diseases characterized by uncontrolled cell growth. … Cancer, Cell Division, Mutation, DNA Error, Metastasis, Tumor, Family …
15 Ways Genomics Influences Our World
Genomics is transforming how we study, diagnose and treat cancer.
… Genomics is transforming how we study, diagnose and treat cancer. … Did you know that we are increasingly able to … genomes have changed? Cancer is caused by changes in your genome, but advances in DNA sequencing technology are leading … Many of the mutations activate genes that normally promote cell growth or break genes that normally prevent cell growth. …
News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… Kyle Davis … For a patient with cancer, two of the most important words in the oncologist's … better understand what mutations - changes to the cancer cell's DNA - may lead to relapse. In recent research … and Functional Genomics Branch at the National Human Genome Research Institute, and their collaborators studied 10 …
Genetic Disorders
Skin cancer is the most common type of cancer in the United States.
… Skin cancer is the most common type of cancer in the United States. An estimated 40 to 50 percent of … cancer at least once. The most common skin cancer is basal cell carcinoma, which accounts for more than 90 percent of …
News Release
The TCGA network describes uterine and bile duct cancer.
… NHGRI Communications and Public Liaison Branch … The Cancer Genome Atlas (TCGA), a program co-funded by the National … in DNA, RNA and proteins that cause the uncontrolled cell growth that is the hallmark of malignant tumors. Last …
Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
… Prostate cancer is the most common cancer in American men aside from skin cancer. One in 6 American men will develop prostate cancer …
News Release
Investigators with The Cancer Genome Atlas Research Network have identified new potential therapeutic targets for a major form of bladder cancer.
… and Public Liaison Branch … Investigators with The Cancer Genome Atlas (TCGA) Research Network have identified new … the p53 tumor suppressor protein, which helps regulate cell division. RTK/RAS is involved in regulating cell growth …
Genetic Disorders
Breast cancer is the second most common cancer in women after skin cancer.
… Breast cancer is the second most common cancer in women after skin cancer. Each year, approximately 200,000 women in the United …
News Release
Stomach cancers fall into four distinct molecular subtypes researchers with The Cancer Genome Atlas Network have found.
… into four distinct molecular subtypes researchers with The Cancer Genome Atlas (TCGA) Network have found. In the study, … component of a protein, PI3-kinase, which is essential for cell growth and division and many other cellular activities …