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- Ethical, Legal and Social Implications (ELSI) Research Program2
- Genetic Architecture of Complex Traits1
- Genome Technology Program2
- Impact of Genomic Variation on Function (IGVF) Consortium1
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium2
- Developmental Genotype-Tissue Expression (dGTEx)1
Event
On November 16-17, 2023, the National Human Genome Institute will co-sponsor a workshop, Advances in the Genetic Architecture of Complex Human Traits, to take a historically grounded and forward-looking approach towards dissecting the genetic architecture of complex traits in humans.
… vs behavioral traits)? If there is a tight coupling of genetics and environment and potentially GxE effects, how … organization? It is generally believed that less complex traits or “intermediate phenotypes” have simpler … Yet, even low-level molecular traits may have surprisingly complex architectures. Do we have the necessary theoretical …
Educational Resources
A complex disease is caused by the interaction of multiple genes and environmental factors.
… Complex Disease … A complex disease is caused by the interaction of multiple … Cancer, Heart Disease, Gene-environment Interactions … A complex disease (or condition), when discussed in the context of genetics, reflects a disorder that results from the …
Research Funding
Building upon a foundation of quantitative genetics laid over a century ago, applying modern genomic approaches to resolve how genetic and non-genetic factors shape variation in human diseases and traits.
… A major goal of human genetics is to decompose the sources of trait variation into … application of genetic findings, especially for the most complex human traits. Fortunately, the growing availability … … To support research into the genetic architecture of complex human traits through investigator-initiated projects, …
Event
Future Webinar Series
… Contacts … Synopsis A major goal of genetics and genomics is to decompose the sources of trait … NHGRI’s workshop “Advances in the Genetic Architecture of Complex Human Traits” is a seminar series picking up where … challenges for delineating and understanding human complex trait genetics. Format A series of one-hour live …
News Release
NHGRI has appointed Neil Hanchard, M.D., Ph.D., as a clinical investigator within the Medical Genomics and Metabolic Genetics Branch (MGMGB) in the Division of Intramural Research. Dr. Hanchard will head the Childhood Complex Disease Genomics Section within the MGMGB.
… Ganguly, Ph.D. … Dr. Hanchard will lead the new Childhood Complex Disease Genomics Section. … The National Human Genome … investigator within the Medical Genomics and Metabolic Genetics Branch (MGMGB) in the NHGRI Division of Intramural Research. Dr. Hanchard will head the Childhood Complex Disease Genomics Section within the MGMGB. “We are …
Staff
Dr. Neil Hanchard is a clinical investigator within the Center for Precision Health Research (CPHR) and head of the Childhood Complex Disease Genomics Section within the CPHR.
… strong family history of hypertension. Although a role for genetics in the development of the disease has been … and natural selection in the Major Histocompatibility Complex. After returning to Jamaica to study sickle cell … and Human genetics at BCM, focusing on the genetics of complex childhood diseases in diverse populations. In …
Educational Resources
Genetic testing is the use of a laboratory test to look for genetic variations associated with a disease.
Educational Resources
Genetic counseling is the professional interaction between a healthcare provider with specialized knowledge of genetics and an individual or family.
… a healthcare provider with specialized knowledge of genetics and an individual or family. … Genetic Counseling, … a healthcare provider with specialized knowledge of genetics and an individual or family. … Educational Resources …
Event
Join us on Wednesday, May 25, as scholars and scientists answer audience questions and address the complexities surrounding historical and present-day eugenics and scientific racism in the context of existing and developing genetic and genomic screening technologies.
… the history of eugenics and scientific racism and their complex legacies in the modern health sciences. The …
Educational Resources
Genetic discrimination is prejudice directed against people who have or may have a genetic disease.