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Dr. Rongling Li is an epidemiologist and program director in the Division of Genomic Medicine at the National Human Genome Research Institute.
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… variant in the duffy antigen receptor for chemokines gene. PLoS Genetics , 5(1): e1000360. 2009. [ PubMed ] CY … epidemiology, electronic medical records, gene-environment interactions, gene-drug interactions … Dr. Rongling Li is an epidemiologist and …
News Release
How well cancer patients fare after chemotherapy can be affected by their social interaction with other patients during treatment.
Educational Resources
Gene environment interaction is an influence on the expression of a trait that results from the interplay between genes and the environment.
… Gene Environment Interaction … Gene environment interaction is an influence on the … … Genes, Environmental Factors, Genetics, DNA … Gene–environment interaction refers to the interplay of genes … function) and the physical and social environment. These interactions influence the expression of phenotypes. For …
Educational Resources
A complex disease is caused by the interaction of multiple genes and environmental factors.
… and environmental factors. … Genes, Cancer, Heart Disease, Gene-environment Interactions … A complex disease (or condition), when … that is more directly caused by mutations in a single gene. Common examples of complex genetic diseases include …
News Release
CRGGH researchers Amy Bentley and Charles Rotimi have just completed a large-scale, multi-ancestry genome-wide analysis of gene × smoking interactions on the concentration of serum lipids, including high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), and triglycerides.
… a large-scale, multi-ancestry genome-wide analysis of gene × smoking interactions on the concentration of serum lipids, including … and triglycerides. … The study was conducted through the Gene-Lifestyle Interactions Working Group of the Cohorts for …
Event
On January 11, 2021, NHGRI and The George Washington University organized an interactive webinar.
Genetic Disorders
Autism is characterized by impaired social interactions, problems with verbal and nonverbal communication and repetitive behaviors.
… developmental disorders characterized by impaired social interactions, problems with verbal and nonverbal … genetic testing such as chromosome analysis and single-gene testing is done. … There is currently no cure for … and 'secondary,' in which a chromosome abnormality, single-gene disorder or environmental agent can be identified. …
News Release
More research must be done to understand the interactions of ancient genes with modern environments.
… Africans and people of African descent. Mutations in the gene APOL1 , for example, evolved to offer protection against … been made but more research must be done to understand the interactions of ancient genes with modern environments," said … diaspora … More research must be done to understand the interactions of ancient genes with modern environments. … …
News Release
Oral history videos feature conversations with genomics researchers and an interactive discussion with the institute's three directors.
… lead to differences in disease susceptibility and variable drug response. This work can inform how medical professionals …
About Genomics
An interactive timeline listing key moments from the history of the project.
… first tool that researchers use to find a disease-causing gene. These maps identify the general area of the chromosome that contains the gene.  1995 Human Genome Project researchers publish a …