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TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
… Steven Benowitz … Media Availability Researchers in The Cancer Genome Atlas (TCGA) Network have made a number … cancer, and shed light on the role of mitochondria and metabolic pathways in cancer. The results also support the … … Rare kidney tumor provides insights on role of metabolic changes in cancer … TCGA researchers have found that …
News Release
Researchers from The Cancer Genome Atlas Research Network identify novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma.
… Steven Benowitz … Researchers from The Cancer Genome Atlas (TCGA) Research Network have identified novel mutations in a well-known cancer-causing pathway in lung … common subtype of lung cancer. Knowledge of these genomic changes may expand the number of possible therapeutic targets …
Staff
Christine Chang is a program director in the Division of Genomic Medicine at the National Human Genome Research Institute.
… Q. Chang, M.P.H. … Christine Chang is a program officer in the Division of Genomic Medicine, joining the National Human Genome Research Institute in 2014. She manages a portfolio of grants in genomic … Analyst program. Prior to joining NHGRI, Ms. Chang was a Cancer Research Training Fellow at the National Cancer …
Genetic Disorders
Inborn errors of metabolism are disorders that cause a block in a metabolic pathway leading to clinically significant consequences.
… is a sequence of chemical reactions that take place in cells in the body. These reactions are responsible for the … (IEM) are a group of disorders that causes a block in a metabolic pathway leading to clinically significant … they also have the disorder. We recommend talking to your metabolic specialist and/or genetic counselor to determine …
Talking Glossary
A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an increased risk for developing cancer
… Cancer-Susceptibility Gene … A cancer-susceptibility gene is … cancer. Individuals who have inherited mutations in certain cancer-susceptibility genes have a lifetime risk … the general population (e.g., BRCA1 / BRCA2 ). Individuals in the high-risk category may benefit from more frequent …
Genetic Disorders
Breast cancer is the second most common cancer in women after skin cancer.
… Breast cancer is the second most common cancer in women after skin cancer. Each year, approximately 200,000 women in the United States are diagnosed with breast cancer, and …
CRGGH is now part of the newly-created Metabolic, Cardiovascular, and Inflammatory Disease Genomics Branch.
… and Global Health (CRGGH) is now part of the newly-created Metabolic, Cardiovascular, and Inflammatory Disease Genomics … Director, Dan Kastner, this reorganization was conducted, in part, to facilitate new "scientific synergies." These … Synergies … Related Content … CRGGH joins NHGRI's Metabolic, Cardiovascular, and Inflammatory Disease Genomics …
Genetic Disorders
Skin cancer is the most common type of cancer in the United States.
… Skin cancer is the most common type of cancer in the United … once. … Skin cancer is the most common type of cancer in the United States. An estimated 40 to 50 percent of …
Research at NHGRI
The Metabolic Medicine Branch houses clinical and laboratory research programs that focus on the development of new therapies for patients with genetic disorders.
… The Metabolic Medicine Branch (MMB) houses clinical and … patients with genetic disorders. … The research conducted in the Metabolic Medicine Branch involves interconnected laboratory …
News Release
The TCGA network describes uterine and bile duct cancer.
… NHGRI Communications and Public Liaison Branch … The Cancer Genome Atlas (TCGA), a program co-funded by the … of Breast Cancer The TCGA data, more than two petabytes in total from 33 cancer types, catalogs all the key genomic changes - the modifications in DNA, RNA and proteins that …