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News Release
Researchers have discovered that FGF21 is elevated in mice with liver disease that mimics the same condition in patients with methylmalonic acidemia.
… into health care treatment, but not in this case," said Charles P. Venditti , M.D., Ph.D., senior author and senior investigator … medical genomics, genetic disorders, gene therapy, Charles Venditti … Researchers have discovered that FGF21 is …
News Release
NIH researchers demonstrated that gene therapy may be the best method for correcting the single faulty gene that causes Niemann-Pick disease, type C1.
… for gene therapy as a treatment for NPC1 disease," said Charles P. Venditti, M.D., Ph.D., senior investigator in the NHGRI … disease, gene therapy, NPC1 gene, William Pavan, Charles Venditti … NIH researchers demonstrated that gene …
News Release
The Physician-Scientist Development Program helps physicians develop research programs dedicated to the disorders they specialize in.
… "The clinical problems are close enough at hand." Charles Venditti, M.D., Ph.D., himself an alumnus of the program, is … programs, Peter McGuire M.D., Leslie Biesecker M.D., Charles Venditti, M.D. Ph.D. … The Physician-Scientist …
News Release
NIH researchers have uncovered a key factor in understanding the elevated cancer risk associated with gene therapy.
… therapy we have developed so far to treat MMA," said Charles Venditti, M.D., Ph.D., senior author and investigator in … adeno-associated virus, AAV, methylmalonic acidemia, MMA, Charles Venditti M.D. Ph.D., AAV and liver cancer … NIH …
News Release
Researchers recommend more rigorous clinical study of dietary management practices for patients with IEMs, which may result in reformulating some medical foods.
… with many succumbing in the first decade of life," said Charles Venditti, M.D., Ph.D., senior investigator and head of the … errors of metabolism, IEMs, methylmalonic acidemia, MMA, Charles Venditti, cobalamin C, cblC, Kevin Strauss M.D., …
News Release
The largest genomic study on type 2 diabetes in Africans to date has recently been published in Nature Communications and reports the most recent findings of the ongoing Africa America Diabetes Mellitus (AADM) study that has been led by Dr. Charles Rotimi for over two decades.
… Diabetes Mellitus (AADM) study that has been led by Dr. Charles Rotimi for over two decades. … The present study, … function of pancreatic beta cells.  In addition to Dr. Charles Rotimi, the stewardship of the multi-country, … Diabetes Mellitus (AADM) study that has been led by Dr. Charles Rotimi for over two decades. … The largest genomic …
News Release
CRGGH researchers Amy Bentley and Charles Rotimi have just completed a large-scale, multi-ancestry genome-wide analysis of gene × smoking interactions on the concentration of serum lipids, including high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), and triglycerides.
… Amy Bentley … CRGGH researchers Amy Bentley and Charles Rotimi have just completed a large-scale, … Ancestral Diversity … CRGGH researchers Amy Bentley and Charles Rotimi have just completed a large-scale, … and triglycerides. … CRGGH researchers Amy Bentley and Charles Rotimi have just completed a large-scale, …
CRGGH is now part of the newly-created Metabolic, Cardiovascular, and Inflammatory Disease Genomics Branch.
… CRGGH Director and NHGRI Senior Investigator, Charles Rotimi, has been selected to serve as the MCIDGB … and Inflammatory Disease Genomics Branch. ​ … Branch Chief Charles Rotimi, Metabolic, Cardiovascular, and Inflammatory …
News Release
African scientists and collaborators gathered in Pointe aux Piments in Mauritius for the 9th Human Health and Heredity in Africa Consortium Meeting.
… on Genomics and Global Health (CRGGH) Director, Dr. Charles Rotimi (front row, fourth from left), and Deputy … and Heredity in Africa Consortium Meeting. … H3Africa, Charles Rotimi, H3Africa Consortium Meeting, President …
Educational Resources
Evolution is the process by which organisms change over time.
… … Genetic Mutation, Genetic Variation, Gene Expression, Charles Darwin, The Origin Of Species, Genes … Evolution, as …