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NIH researchers identified a novel role for a gene known as heat shock protein 60, finding it is critical in tissue regeneration and wound healing.
… bacterial infection from a cut. "A major problem is that diabetes inhibits wound healing," said Dr. Burgess. "The … and may lead to hospitalization or even amputation. Diabetes is the leading causes of non-traumatic lower limb … any wound heal, not just wounds encountered by people with diabetes. Will it reduce scarring and increase the speed of …
Staff
Dr. Michael Erdos is an Associate Investigator in the Molecular Genetics Section of the Center for Precision Health Research.
… impact and functional basis of risk variants for type 2 diabetes (T2D). That information can both provide predictive … US Investigation of NIDDM (FUSION), non-insulin dependent diabetes mellitus (NIDDM) genetics study and in the … in the Accelerating Medicines Partnership in Type 2 Diabetes (AMP-T2D) consortium. … The application of genetic, …
Staff
Dr. Francis Collins is a senior investigator in Center for Precision Health Research.
… cancer syndrome, and most recently, genes for type 2 diabetes, and the gene that causes Hutchinson-Gilford … complex, common, non-Mendelian condition known as type 2 diabetes (T2D). In long-term cooperation with researchers at … critical insight into the molecular mechanisms involved in diabetes susceptibility. … Tenney AP, Di Gioia SA, Webb BD, …
Research at NHGRI
Families Sharing Health Assessment and Risk Evaluation (SHARE) helps you and your family learn how your family health history affects your risk for diseases.
… Colorectal Cancer Breast Cancer Prostate Cancer Type 2 Diabetes Heart Disease How to Use the Families SHARE Risk … and healthy guidelines to reduce risk of heart disease, diabetes, breast cancer, and colorectal cancer . BMC Public …
The Genomics Landscape
In March 2, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., honors the recipients of the inaugural Outstanding Award for Enhancing DEIA in the Genomics Workforce - Pardis Sabeti (Harvard University), Bettie Graham (NHGRI) and Ann Mc Cartney (University of California, Santa Cruz) - for exemplifying powerful ways to promote diversity, equity, inclusion and accessibility.
… Nile rat facilitates exploration of the genetic basis of diabetes Toh et al. BMC Biol 20, 245 (2022). PMC9641963 The Nile rat is a promising resource for diabetes research. Other rodent species require genomic modifications to model diabetes and cannot properly model pre-diabetes or early …
Profile
NHGRI researchers recently published a study using virtual reality simulations to investigate how clinicians might use a type of genomic risk information called polygenic risk scores in medical care.
… to recommend observing kidney function and screening for diabetes in response to the patient’s symptoms when they had … that participants were more likely to recommend assessing diabetes when the patient was Black, which is in line with racial disparities in diabetes rates in the United States. In a couple cases, the …
Profile
Reflecting on his NIH career, Dr. Smith recounts his journey from researcher to program director in a conversation with NHGRI science writer Sonja Soo, Ph.D. He looks ahead to a retirement filled with traveling, spending time with friends and family, playing pickleball and brewing ale.
… genes and studied conditions such as kidney failure and diabetes. Some high points were performing the analyses … studied conditions such as kidney failure, HIV/AIDS and diabetes. Reflecting on his NIH career, Dr. Smith recounts …
The Genomics Landscape
In the April 2024 issue of The Genomics Landscape, NHGRI Director Eric Green details how the Office of Genomic Data Science (OGDS) is becoming the epicenter for genomic data science at the institute, with numerous collaborations, projects and activities.
… reveals molecular signatures associated with type 2 diabetes in Nigerians Doumatey, et al. Genome Med ., 2024 … that about 500 million people worldwide have type 2 diabetes. However, studies of this condition have mostly been … or other materials—in people with and without type 2 diabetes in Nigeria. This is the largest such study in an …
The Genomics Landscape
In the July 7, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., emphasizes the importance of the Technology Transfer Office and its mission to manage all the legal negotiations that help to protect federally funded research from being unduly exploited, while also giving that research avenues to reach patients through the commercialization of promising advances.
… “The FUSION Study: Mapping Genes for Non-Insulin Dependent Diabetes Mellitus - Tissue Biopsy Study” is a long-term, … to identify genomic variants that predispose to type 2 diabetes. Nearly 60 other researchers have used this dataset … a variety of topics: chronic complex diseases, type 2 diabetes, epigenomics, aging, cancer, data privacy, and …
Educational Resources
A complex disease is caused by the interaction of multiple genes and environmental factors.
… of complex genetic diseases include heart disease, diabetes, and cancer. … A complex disease is caused by the …