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Research at NHGRI
The Translational and Functional Genomics Branch explores the genetic, epigenetic and metagenomic basis of human disorders.
… The Translational and Functional Genomics Branch (TFGB) studies how genome … in genetics and computational genomics, including functional assessment, systematic mutagenesis, developmental … and computational analysis of both human and microbial DNA. By testing approaches and technologies in cell lines and …
Staff
Dr. Laura Elnitski is a senior investigator in the Translational and Functional Genomics Branch at the National Human Genome Research Institute.
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… look at multi-species comparisons of noncoding regulatory elements. She was awarded a Ruth L. Kirschstein National … and chicken, as well as the ENCODE Consortium to elucidate functional elements in the human genome. Her work specializes … PLoS ONE ). A heat map depicting the stratified levels of DNA methylation in a variety of gynecological tissues and …
The Genomics Landscape
In the September 3, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about the Impact of Genomic Variation on Function (IGVF) Consortium, the 2020 Genomic Innovator Awards and more.
… relationships to relevant genes and their regulatory elements, cell types, and biological pathways. The IGVF … finding and characterizing genomic variants, the genomic elements in which they reside or affect, and the influences … The IGVF Consortium will encompass five components: Functional Characterization Centers, Regulatory Network …
Jobs at NHGRI
Funded postdoctoral positions are available in the laboratory of Dr. Shawn Burgess, within NHGRI's Translational and Functional Genomics Branch.
… of Shawn Burgess, Ph.D., within the Translational and Functional Genomics Branch of the National Human Genome … … The focus of the Burgess lab is on the genetics and functional genomics of tissue regeneration and wound healing … … Position Description … Qualifications … How to Apply … Functional Genomics of Tissue Regeneration … Funded …
Educational Resources
DNA replication is the process by which a molecule of DNA is duplicated.
… DNA Replication … DNA replication is the process by which a molecule of DNA is duplicated. … DNA, Cell Division, Cell Biology … DNA replication is the …
Educational Resources
DNA sequencing is a laboratory technique used to determine the exact sequence of bases (A, C, G, and T) in a DNA molecule.
… DNA Sequencing … DNA sequencing is a laboratory technique used to determine … the exact sequence of bases (A, C, G, and T) in a DNA molecule. … Adenine, Cytosine, Guanine, Thymine, ACGT, DNA, DNA Sequencing … DNA sequencing refers to the general …
Media Availability
Researchers find that more than 80 percent of mouse genes had variations in the nearby regulatory DNA that affects gene activity.
… in many genes themselves play a role, small variations in DNA sequences near genes that control when and how much a … Medicine, NHGRI; Andrea Beckel-Mitchener, Ph.D., chief, Functional Neurogenomics Program, Division of Neuroscience … grasp wider role for genetic variation in regulatory elements of genome … Researchers find that more than 80 …
Fact Sheets
A DNA microarray is a tool used to determine whether the DNA from a particular individual contains a mutation in genes.
… The DNA microarray is a tool used to determine whether the DNA from a particular individual contains a mutation in … that a mutation - or alteration - in a particular gene's DNA may contribute to a certain disease. However, it can be …
Educational Resources
Mitochondrial DNA is the small circular chromosome found inside mitochondria.
… Mitochondrial DNA … Mitochondrial DNA is the small circular chromosome found inside mitochondria. … Mitochondrial DNA, Mitochondria, Cell Biology, Inheritance … Mitochondrial …
Educational Resources
Recombinant DNA Technology is a technology that uses enzymes to cut and paste together DNA sequences of interest.
… Recombinant DNA Technology … Recombinant DNA Technology is a technology that uses enzymes to cut and paste together DNA sequences of interest. … Cell, Deoxyribonucleic Acid …