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Gene mapping is the process of establishing the locations of genes on the chromosomes.
… mapping is the process of establishing the locations of genes on the chromosomes. … Chromosomes, Linkage Analysis, … refers to the process of determining the location of genes on chromosomes. Today, the most efficient approach for gene mapping involves sequencing a genome and then using computer programs to analyze the sequence to …
Educational Resources
Gene amplification is an increase in the number of copies of a gene sequence.
Educational Resources
A tumor suppressor gene directs the production of a protein that is part of the system that regulates cell division.
… it encodes is not produced or does not function properly, and as a result, uncontrolled cell division may occur. Such …
Educational Resources
Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule.
… be thought of as an “on/off switch” to control when and where RNA molecules and proteins are made and as a … and cell types. The RNA and protein products of many genes serve to regulate the expression of other genes. Where, when, and how much a gene is expressed can also …
Talking Glossary
La interacción genes–ambiente se refiere a interrelación de los genes (y en términos más amplios, de la función del genoma) y el entorno físico y social.
… Interacción genes-ambiente … La interacción genes–ambiente se refiere a interrelación de los genes (y en … interaction refers to the interplay of genes (and, more broadly, genome function) and the physical and …
News Release
A new method of targeting specific DNA sequences in zebrafish could accelerate the discovery of gene function and the identification of disease genes in humans.
… dramatically accelerate the discovery of gene function and the identification of disease genes in humans, according to scientists at the National … effective than other techniques at homing in on target genes and inserting or deleting specific sequences. The study …
News Release
NHGRI researchers identified 59 genes or gene regions linked to canine athletics.
… of canine genomics, sport hunting dogs are super athletes and terriers are plucky supermodels. National Human Genome … researchers reached this conclusion after identifying 59 genes or gene regions linked to canine athletics, including … moustache and eyebrows. Gene variants associated with autism-like behaviors, hyperactivity and panic responses in …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data.
… cell fates or cell states. They use the gene expression and functional element data to construct gene regulatory … from one physiologic state to another. They derive and test predictions from the models, to determine the … data to understand what elements are controlling what genes, in what cell types. The ability to make accurate …
Talking Glossary
A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an increased risk for developing cancer
… have inherited mutations in certain cancer-susceptibility genes have a lifetime risk of cancer that is significantly …
News Release
NIH researchers demonstrated that gene therapy may be the best method for correcting the single faulty gene that causes Niemann-Pick disease, type C1.
… at NIH's National Human Genome Research Institute (NHGRI) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, was published Oct. 26, 2016, in the … Human Molecular Genetics . Niemann-Pick disease is a rare and fatal disorder of the central nervous system (the brain …