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News Release
NIH Center for Research on Genomics and Global Health is participating in the H3Africa Consortium's effort to develop an African-specific genotyping array.
… , for example, evolved to offer protection against the pathogen that causes African sleeping sickness, but today …
Educational Resources
An animal model is a non-human species used in medical research because it can mimic aspects of a disease found in humans.
… like humans in their anatomy, physiology or response to a pathogen that researchers can extrapolate the results of …
News Release
Researchers at NHGRI have discovered an immune mechanism in humans that perceives threats and was found only in plants.
… instead of immune molecules sensing and responding to a pathogen directly, which was thought to be the sole counter … molecules and white blood cells to annihilate the pathogen - a response, in some cases, that's orchestrated by … through a single mechanism, instead of developing pathogen-specific defenses, Dr. Chae explained. Studies like …
News Release
NIH has awarded grants of more than $28 million aimed at deciphering the language of how and when genes are turned on and off.
… that the dendritic cell undergoes when it encounters a pathogen, including the genes that are turned on and off, … white blood cell called a macrophage reacts to a bacterial pathogen, which can result in the activation of more than …
Research Funding
The Genomics of Gene Regulation project develops methods to construct predictive, accurate gene regulatory network models using genomic data​​.
Staff
Dr. Sean Conlan is an associate investigator in the Translational and Functional Genomics Branch at the National Human Genome Research Institute.​
… Holland SM. Adaptability and persistence of the emerging pathogen Bordetella petrii . PLoS One, 8(6): e65102. 2013 . [ …
Research Funding
The Knockout Mouse Phenotyping Project (KOMP2) collaborates with the International Mouse Phenotyping Consortium (IMPC) to knockout and characterize all protein-coding genes in the mouse genome.
FAQ
Questions and answers to help applicants responding to the ML/AI Tools to Advance Genomic Translational Research (MAGen) notice of funding opportunities (NOFOs): RFA-HG-24-004 and RFA-HG-24-005.
News Release
NHGRI researchers have discovered that Mediterranean populations may be more susceptible to an autoinflammatory disease because of evolutionary pressure to survive the bubonic plague.
… function of pyrin in healthy individuals. In doing so, the pathogen suppresses the body's inflammatory response to the … increase patients' survival rate when infected by the pathogen. To test this hypothesis, the researchers …
15 Ways Genomics Influences Our World
Genomics is empowering farmers to improve the food supply.