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- Genome Technology Program4
- Impact of Genomic Variation on Function (IGVF) Consortium3
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)2
- Developmental Genotype-Tissue Expression (dGTEx)1
- Ethical, Legal and Social Implications (ELSI) Research Program4
- Genomics-Enabled Learning Health Systems (gLHS)1
News Release
The Human Genome Project has been awarded the 2017 Prince Mahidol Award for ground-breaking advances in the field of medicine.
… Sheena Faherty, Ph.D. … The Human Genome Project has been awarded the 2017 Prince Mahidol Award for … of medicine. The award will be received on behalf of the project by Eric Green, M.D., Ph.D., director of the National … the institute responsible for leading NIH's effort in the project. … The Human Genome Project, completed in 2003, was …
Educational Resources
In genomic imprinting the ability of a gene to be expressed depends upon the sex of the parent who passed on the gene.
… Sequence, Genes, Family Health History, Genealogy, Gene Expression … Genomic imprinting is the process by which only … does not affect the DNA sequence itself. Instead, gene expression is silenced by the epigenetic addition of chemical …
For Teachers
Tools and resources for teaching the concepts of transcription and translation, two key steps in gene expression
… of transcription and translation, two key steps in gene expression . … Transcription is the process of making an RNA … by including more complex problems and aspects of gene expression, such as the excision of introns." See: Decoding … of transcription and translation, two key steps in gene expression. … Teaching Transcription, Teaching Translation, …
About Genomics
In 2003, an accurate and complete human genome sequence was finished two years ahead of schedule and at a cost less than the original estimated budget.
… researchers two years ahead of the original Human Genome Project schedule and at a cost less than the original … of genes are expressed as messenger RNA in a particular tissue, and how a cell's regulatory networks control vast … Human Genome Sequencing, Long-range Planning, Gene Expression, Sequence Variations, Phenotypes, Large-scale …
Research Funding
The Encyclopedia of DNA Elements (ENCODE) Pilot Project launched in September 2003 to identify all functional elements in the human genome sequence.
… of DNA Elements (ENCODE) in September 2003 to carry out a project to identify all functional elements in the human … analyzed because of failed design or failed genotyping. Genotype data were obtained from the remaining 20,000 SNPs in … data set because of the high density of SNP coverage. The genotype data from these regions will be used to determine …
Virtual Exhibit
The Human Genome Project changed traditional understandings of how and why scientific research is conducted. It was, however, not without its detractors. Early in 1990, there was an effort to stop funding for the nascent Human Genome Project, in the form of a letter writing campaign.
… letter, which circulated and spurred the anti-Human Genome Project letter campaign. The first line of the letter reads “The human genome project: mediocre science, terrible science policy.” … … of the genome do indeed provide valuable functions in gene expression, among other things. There are still many …
About Genomics
The Human Genome Project was an inward voyage of discovery led by an international team of researchers looking to sequence and map all the genes of our species.
… The Human Genome Project (HGP) is one of the greatest scientific feats in history. The project was a voyage of biological discovery led by an … October 1990 and completed in April 2003, the Human Genome Project’s signature accomplishment – generating the first …
Fact Sheet
A fact sheet detailing how the project began and how it shaped the future of research and technology.
… The human genome sequence generated by the Human Genome Project was actually a patchwork of multiple people whose … of mostly European ancestry. … How did the Human Genome Project affect biological research in general? The Human Genome Project demonstrated that production-oriented, …
News Release
The Encyclopedia of DNA Elements (ENCODE) Project has created a detailed resource on the letters of life, DNA, identifying genes and regions that may regulate genes in the human and mouse genomes.
… Prabarna Ganguly, Ph.D. … ENCODE Project's third phase offers new insights into the … and genome … The Encyclopedia of DNA Elements (ENCODE) Project is a worldwide effort to understand how the human … outside of protein-coding regions can influence the expression of genes, even genes located far away from a …
The Genomics Landscape
In the June 2019 edition of The Genomics Landscape, NHGRI Director Eric Green details the legacy of the Human Microbiome Project as it reaches completion.
… catalyzed the launching of the NIH Human Microbiome Project (HMP). In 2007, the NIH Common Fund initiated the HMP … multiple initiatives, including the International HapMap Project , the 1000 Genomes Project , the Genomic Resources Program, the Centers of …