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The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… thyroid carcinomas (PTC) - the most common form of thyroid cancer - has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive disease … diagnosis and treatment. … WHAT: Investigators with The Cancer Genome Atlas (TCGA) Research Network identified new …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… … In the largest genomics study of clear cell endometrial cancer (CCEC) tumors to date, National Human Genome Research … tumors are sometimes similar to other types of uterine cancer, namely serous endometrial cancers or endometrioid … The study was published May 9, 2017, in the journal Cancer . … Largest Study of Its Kind Endometrial cancer is …
News Release
How well cancer patients fare after chemotherapy can be affected by their social interaction with other patients during treatment.
… Jeannine Mjoseth … How well cancer patients fare after chemotherapy can be affected by … and the University of Oxford in the United Kingdom. … Cancer patients were a little more likely to survive for five … out to see if the impact of social interaction extended to cancer patients undergoing chemotherapy. Joining this …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… in tumor DNA that occurs in five different types of cancer. They also found evidence that this methylation signature may be present in many more types of cancer. The specific signature results from a chemical … from patients with bladder, breast, colon, pancreatic and prostate cancers to determine the accuracy of detection at …
News Release
Researchers from The Cancer Genome Atlas Research Network identify novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma.
… Steven Benowitz … Researchers from The Cancer Genome Atlas (TCGA) Research Network have identified novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma, the most common subtype of lung cancer. Knowledge of these genomic changes may expand the …
News Release
A repurposed cancer drug appears to reduce the severity of lesions and pain experienced by people with Proteus syndrome
… Jeannine Mjoseth … A repurposed cancer drug appears to reduce the severity of lesions and … goal in using the drug was very different from its use in cancer therapy. In cancer, the objective is to eliminate all cancerous cells …
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… The Cancer Genetics and Comparative Genomics Branch seeks to … the development of various aggressive cancers, including prostate, endometrial, bladder, lung, head and neck, and … of cancer, including (but not limited to) cancers of the prostate, endometrium, lung, bladder, and breast; melanoma, …
Talking Glossary
A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an increased risk for developing cancer
… Cancer-Susceptibility Gene … A cancer-susceptibility gene is a gene that, when changed (or … gives an individual an increased risk for developing cancer … A cancer-susceptibility gene is a gene that, when …
Talking Glossary
Un gen de susceptibilidad al cáncer es un gen que, cuando cambia (o muta) confiere a la persona un mayor riesgo de desarrollar cáncer.
… a la persona un mayor riesgo de desarrollar cáncer. … A cancer-susceptibility gene is a gene that, when changed (or … gives an individual an increased risk for developing cancer. Individuals who have inherited mutations in certain cancer-susceptibility genes have a lifetime risk of cancer …
News Release
NIH-funded researchers completed the PanCancer Atlas from over 10,000 tumors representing 33 types of cancer.
… from over 10,000 tumors representing 33 types of cancer. … More than 10,000 Tumors Analyzed "This project is … Francis S. Collins, M.D., Ph.D. "This analysis provides cancer researchers with unprecedented understanding of how, … informed clinical trials and future treatments." The Pan-Cancer Atlas, published as a collection of 27 papers across a …