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News Release
NHGRI researcher Dr. Julie Segre has been elected to the National Academy of Medicine, one of the highest honors in the fields of health and medicine.
… to investigate healthcare-associated outbreaks of multi-drug resistant bacteria. Dr. Segre published foundational … tools to track hospital-acquired infections of multi-drug resistant organisms, including the cluster of infections …
Research Training
A fellowship that will prepare fellows to use genetic, genomic and pharmacogenomic approaches to advance minority health and health equity.
… Genome Research Institute (NIH NHGRI) and the Food and Drug Administration’s Office of Minority Health and Health … working closely with mentors at both FDA OMHHE, Center for Drug Evaluation and Research (CDER) and NIH NHGRI, providing …
Profile
An interview with Meru Sadhu, an Earl Stadtman Investigator and head of the systems biology and genome engineering section within the NHGRI Intramural Research Program, where he talks about his research and why yeast have a special place in his heart.
News Release
The skin microbiota plays an intricate role in the human immune system, directing many immune functions and defending against bacterial pathogens.
News Release
NIH investigators have discovered that genomic switches of a blood cell are key to regulating the human immune system.
… arthritis. When the scientists exposed human T cells to a drug used to treat the disease, tofacitinib, the activities … and the pharmacological effects of a rheumatoid arthritis drug-are all pointing to the importance of super-enhancers," …
News Release
A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers.
… to combat BRAF -associated cancers and seeking ways around drug resistance. Moreover, "because of the very high …
The Genomics Landscape
In the January 2018 edition of The Genomics Landscape, NHGRI Director Eric Green features the NIH Intramural Sequencing Center.
… to genomics: " pinpoint gene editing ," " a cancer drug's broad swipe ," and " gene therapy triumph ." Nature's …
News Release
Over the last 20 years, three families have been unknowingly linked to one another by an unknown illness. Researchers at the National Human Genome Research Institute (NHGRI) and other organizations have now identified the cause of the illness, a new disease called CRIA syndrome. The results of their work were published on Dec. 11 in the journal Nature.
… had little effect on the patients, one biological drug called tocilizumab did. Tocilizumab, a drug that suppresses the immune system, reduced the severity …
News Release
Researchers from The Cancer Genome Atlas Research Network identify novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma.
Genetic Disorders
Familial hypercholesterolemia is an inherited condition causing increased low density lipoprotein cholesterol at birth and heart attacks at an early age.
… lose weight, may also help in lowering cholesterol levels. Drug therapy is usually necessary in combination with diet, … their significantly elevated levels of cholesterol. Often drug therapies are not sufficient to lower LDL cholesterol …