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News Release
An ancient, sexually transmitted dog cancer may provide insights into human cancers because of the similarities in the dog and human immune systems.
… Steven Benowitz … An ancient, sexually transmitted dog cancer - that may provide insights into human cancers because … genes will prove critically important in understanding early stages of tumor growth in humans."  Dr. Ostrander, … functioning dog immune system? We're interested in the early process that has gone awry." Current human cancer …
News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… Kyle Davis … For a patient with cancer, two of the most important words in the oncologist's … hear the word remission - meaning both their symptoms and cancer are abating. Some may even get to full remission - no detectable cancer. But, unfortunately, some patients will hear the word …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… … In the largest genomics study of clear cell endometrial cancer (CCEC) tumors to date, National Human Genome Research … tumors are sometimes similar to other types of uterine cancer, namely serous endometrial cancers or endometrioid … endometrioid endometrial cancer, tends to diagnosed early and generally responds well to treatment; the five-year …
Media Availability
The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… thyroid carcinomas (PTC) - the most common form of thyroid cancer - has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive disease … diagnosis and treatment. … WHAT: Investigators with The Cancer Genome Atlas (TCGA) Research Network identified new …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… in tumor DNA that occurs in five different types of cancer. They also found evidence that this methylation … test that can be used to diagnose a variety of cancers at early stages, when treatments can be most effective. The … that uncovered telltale methylation marks in colon, lung, breast, stomach and endometrial cancers. They showed that all …
News Release
How well cancer patients fare after chemotherapy can be affected by their social interaction with other patients during treatment.
… Jeannine Mjoseth … How well cancer patients fare after chemotherapy can be affected by … and the University of Oxford in the United Kingdom. … Cancer patients were a little more likely to survive for five … out to see if the impact of social interaction extended to cancer patients undergoing chemotherapy. Joining this …
News Release
Researchers from The Cancer Genome Atlas Research Network identify novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma.
… Steven Benowitz … Researchers from The Cancer Genome Atlas (TCGA) Research Network have identified novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma, the most common subtype of lung cancer. Knowledge of these genomic changes may expand the …
News Release
A repurposed cancer drug appears to reduce the severity of lesions and pain experienced by people with Proteus syndrome
… Jeannine Mjoseth … A repurposed cancer drug appears to reduce the severity of lesions and … "The results were so encouraging that we ended the study early, so we can begin the next one to determine the … goal in using the drug was very different from its use in cancer therapy. In cancer, the objective is to eliminate all …
Talking Glossary
A cancer-susceptibility gene is a gene that, when changed (or mutated), gives an individual an increased risk for developing cancer
… Cancer-Susceptibility Gene … A cancer-susceptibility gene is a gene that, when changed (or … gives an individual an increased risk for developing cancer … A cancer-susceptibility gene is a gene that, when …
Research at NHGRI
The NHGRI Cancer Genetics and Comparative Genomics Branch identifies and study genes that contribute to cancer susceptibility and progression.
… The Cancer Genetics and Comparative Genomics Branch seeks to identify and study genes that contribute to cancer susceptibility and progression. … The branch focuses … cancers of the prostate, endometrium, lung, bladder, and breast; melanoma, and Fanconi anemia. These research efforts …