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News Release
NHGRI researchers seek help from people with Sickle Cell Disease to find the factors - environmental, social and genetic - that impact the severity of symptoms.
… are seeking help from people affected by SCD to find the factors - environmental, social and genetic - that impact the … the genes in a person), and the social and environmental factors that may impact their symptoms. Mr. Bonham is … role of stress, the impact of the microbiome and social factors on health status and quality of life." In addition, …
Staff
Jennifer Strasburger was the lead Genomic Program Administrator (GPA) for NHGRI as well as the co-chair for the NHGRI Data Access Committee (DAC).
… Strasburger, Data Access Committee (DAC), informatics, epigenetic, epitranscriptomics … Jennifer Strasburger was the …
News Release
Genomic variants that increase risk of kidney disease are found in nearly one-third of West Africans
A study from researchers at National Institutes of Health (NIH) and their collaborators revealed a significant genetic risk factor for kidney disease in people of West African ancestry.
… to develop the disease. Both genetic and environmental factors, which includes social factors, such as smoking, lack of exercise, an unhealthy diet …
Educational Resources
Gene regulation is the process of turning genes on and off.
… on and off. … Gene Expression, Genes, DNA, Transcription Factors … Gene regulation is the process used to control the …
News Release
Researchers build a statistical model using family health history to improve disease risk assessment
Researchers at the National Human Genome Research Institute (NHGRI) have developed a new statistical model that can predict the risk for developing diseases by combining information about family member health and lifestyle factors from family members.
… members about their family health history and lifestyle factors. … Published in March in the peer-reviewed journal … information about family member health and lifestyle factors from family members. … Researchers at the National … information about family member health and lifestyle factors from family members. … News Release …
Health
Knowledge of your family health history can help you and your healthcare providers identify patterns of inheritance and risk factors.
… providers identify patterns of inheritance and risk factors. … Modernizing family health history: achievable … providers identify patterns of inheritance and risk factors. … Health …
News Release
Researchers analyzing human, fly, and worm genomes have found these species have key genomic processes in common, reflecting their shared ancestry.
… regulation. Scientists focused on transcription-regulatory factors, key protein regulators that determine which … One of the big questions in genomics is to determine what factors work together to turn on which genes," said co-senior … California. Investigators found that the transcription factors tend to bind to similar DNA sequences in the three …
News Release
In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.
Research Funding
Building upon a foundation of quantitative genetics laid over a century ago, applying modern genomic approaches to resolve how genetic and non-genetic factors shape variation in human diseases and traits.
… the sources of trait variation into constituent causal factors. The hope is to better understand both the … and interpret the interplay of genetic and non-genetic factors on trait variation. These issues have recently risen … genomic approaches to resolve how genetic and non-genetic factors shape variation in human diseases and traits. … …
Research Training
The NHGRI Social and Behavioral Research Branch invites recent graduates to pursue multidisciplinary training in genomics and health.
… in SBRB investigate social, behavioral, and ethical factors that facilitate translation of genomic discoveries … Training In Genomics And Health, Social/behavioral/ethical Factors, Genomic Discoveries, Health Promotion, Disease …