Search Results
Facet (Page)
Refine Your Search
Audiences
Content Formats
Events
Sections
Divisions
Programs
- Genome Technology Program2
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Genomic Innovator Awards1
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium1
- Ethical, Legal and Social Implications (ELSI) Research Program2
- Genomics-Enabled Learning Health Systems (gLHS)1
Educational Resources
BRCA1 and BRCA2 are the first two genes found to be associated with inherited forms of breast cancer.
… BRCA1/BRCA2 … BRCA1 and BRCA2 are the first two genes found to be associated with inherited forms of breast cancer. … Breast Cancer, Prostate Cancer, Genetic Mutation, …
Genetic Disorders
Prostate cancer is a disease where certain cells in the prostate become abnormal and multiply to form a tumor.
… Prostate cancer is the most common cancer in American men aside from … risk factor for prostate cancer. It is rare for a man to develop prostate cancer before the age of 40. After age 50 … has hereditary prostate cancer - cancer that is caused by genes inherited from their parents. Hereditary prostate …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… called methylation, which can control the expression of genes like a dimmer on a light switch. … Higher amounts of … activity. Based on this advance, the researchers hope to spur development of a blood test that can be used to … by 99 percent, the computer could still detect the cancer-related methylation marks in the mixture. Knowing that tumors …
Educational Resources
Gene regulation is the process of turning genes on and off.
… Gene Regulation … Gene regulation is the process of turning genes on and off. … Gene Expression, Genes, DNA, Transcription Factors … Gene regulation is the process used to control the timing, location and amount in which genes are …
News Release
NIH scientists proposed a new approach for finding ways to impede or halt cancer's spread: transgenic zebrafish as a live animal model of metastasis.
… - the migration of cancer cells from the original tumor to other places in the body. In at least 90 percent of … genome has close counterparts to about 70 percent of human genes. Another feature makes the zebrafish especially … useful in this way." … New Approach to Fight Metastasis … Related Content … Zebrafishing for a weapon against …
News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… are elusive. Without information, the patient may decide to treat a benign tumor with harsh drugs or risky surgery or … In healthy cells, these flags are correctly placed and genes are expressed in the right proportions. However, in … 2015. [ Full Text ] … Analysis of Tumors Yields Insights … Related Content … Studying cancer from the inside out: What …
News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… their symptoms and cancer are abating. Some may even get to full remission - no detectable cancer. But, unfortunately, … as a huge DNA "book" in each cell that includes all of our genes (the chapters), and provides all the instructions for … 2015. [ Full Text ] … Why do Leukemia Patients Relapse? … Related Content … Investigating why cancer comes back … …
News Release
A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers.
… in medical breakthroughs, whether by mushing across Alaska to deliver diphtheria antitoxin serum or by serving alongside … our aid-as a powerful animal model for research into human cancer. … A genetic mutation that triggers bladder cancer in … Cancer Research , March 12, 2015. … A Power Animal Model … Related Content … Dogs may help researchers sniff out new …
News Release
NHGRI researchers have identified new genes associated with the Erdheim-Chester disease (ECD) and some possible new therapies.
… Research Institute (NHGRI) researchers have identified new genes associated with the Erdheim-Chester disease (ECD) and … Program . "Our work on ECD builds on the institute's goals to advance medical knowledge about rare diseases and to … # NCT02281760 ). … Advancing Medical Knowledge … Related Content … Genes associated with Erdheim-Chester …
News Release
An ancient, sexually transmitted dog cancer may provide insights into human cancers because of the similarities in the dog and human immune systems.
… or CTVT, spreads when cancer cells move from one dog to the other during sexual contact, without the help of a … in the journal Genome Research . "We figured out which genes the tumor modified so that it could escape the host … 2015. [ PubMed ] … Understanding Tumor Growth … Related Content … An ancient tumor in dogs might teach new …