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News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… Kyle Davis … For a patient with cancer, two of the most important words in the oncologist's lexicon begin with the letter "r": … rules will help doctors better understand what mutations - changes to the cancer cell's DNA - may lead to relapse. In …
News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… Kyle Davis … Receiving a cancer diagnosis can feel like losing control of everything. In the wake of such a diagnosis, patients, family and friends … Will it spread? Sometimes doctors can offer answers, but in other cases they are elusive. Without information, the …
News Release
A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers.
… Mjoseth … Over the years, domestic dogs have figured in medical breakthroughs, whether by mushing across Alaska to … our aid-as a powerful animal model for research into human cancer. … A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in …
News Release
An ancient, sexually transmitted dog cancer may provide insights into human cancers because of the similarities in the dog and human immune systems.
… Steven Benowitz … An ancient, sexually transmitted dog cancer - that may provide insights into human cancers because of the similarities in the dog and human immune systems - has baffled researchers … cells. They reported their results online July 31, 2015, in the journal Genome Research . "We figured out which genes …
News Release
NHGRI has selected Charles Venditti, M.D., Ph.D., as chief of its Metabolic Medicine Branch within the Institute’s Intramural Research Program. In this role, he will provide leadership and guidance on research into genetic diseases that disrupt metabolism.
… selected Charles P. Venditti, M.D., Ph.D., as chief of its Metabolic Medicine Branch within the Institute’s Intramural Research Program. In this role, he will provide leadership and guidance on … in the basic, translational and clinical aspects of metabolic diseases,” said Charles Rotimi, Ph.D., NHGRI …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… NHGRI Communications and Public Liaison Branch … In the largest genomics study of clear cell endometrial cancer (CCEC) tumors to date, National Human Genome Research … build a knowledge base to decipher the fundamental genomic changes that drive these cancers." Dr. Bell and her team …
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The Cancer Genome Atlas identified molecular subtypes to help clinicians determine which tumors are more aggressive and which will respond to treatment.
… thyroid carcinomas (PTC) - the most common form of thyroid cancer - has provided new insights into the roles of … confirmed that PTCs are driven primarily by mutations in one of two cancer-associated genes: BRAF (and a particular … differences between the two genetic types, particularly in signaling pathways that promote tumor development and …
News Release
How well cancer patients fare after chemotherapy can be affected by their social interaction with other patients during treatment.
… Jeannine Mjoseth … How well cancer patients fare after chemotherapy can be affected by … Institutes of Health, and the University of Oxford in the United Kingdom. … Cancer patients were a little more … years or more. Patients were a little more likely to die in less than five years after chemotherapy when they …
News Release
A repurposed cancer drug appears to reduce the severity of lesions and pain experienced by people with Proteus syndrome
… Jeannine Mjoseth … A repurposed cancer drug appears to reduce the severity of lesions and … disease. The drug, miransertib, was well tolerated, even in children, according to a National Institutes of Health … Biesecker, M.D., chief of the NHGRI Medical Genomics and Metabolic Genetics Branch and the study's corresponding …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… of Health researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer. They also found evidence that this methylation …