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News Release
Grants are awarded to GTEx project to explore human gene expression and regulation in different tissues, and how genomic variation modulates that expression.
… and the proteins that cells produce based on such regulation. To do this, scientists will examine part of the … Ph.D. To gauge the influence of genetic variation on gene regulation and expression in different cells and tissues, … to examine certain areas in the genome and gauge gene regulation within tissue samples from various ethnic groups. …
News Release
American Indians and Alaska Natives IRB training programs at NIH ensure the welfare of people participating in federally regulated research.
Staff
Rebecca Hong is a scientific program analyst in the Policy and Program Analysis Branch at the National Human Genome Research Institute.
… project management. The focus areas of her work are FDA regulation of genomic technologies and U.S. science policy … … Rebecca Hong, B.S. … Rebecca Hong, genomic policy, FDA regulation, genomic technology, legislation, AIDS research, … genome editing … Rebecca Hong, genomic policy, FDA regulation, genomic technology, legislation, AIDS research, …
News Release
The Encyclopedia of DNA Elements (ENCODE) Project has created a detailed resource on the letters of life, DNA, identifying genes and regions that may regulate genes in the human and mouse genomes.
… third phase offers new insights into the organization and regulation of our genes and genome … The Encyclopedia of DNA … identify and characterize their functional roles in gene regulation. "A key challenge in ENCODE is that different … benefited from and built upon decades of research on gene regulation performed by independent researchers around the …
News Release
Researchers have found powerful clues to why certain processes and systems in the mouse are so different from those in people.
… from those in people. Building on years of mouse and gene regulation studies, they have developed a resource that can … used." In the Nature papers, the researchers compared gene transcription, chromatin modification and other processes … in a wide range of mouse and human tissues and cell types. Transcription is the process by which a gene's instructions …
News Release
Researchers analyzing human, fly, and worm genomes have found these species have key genomic processes in common, reflecting their shared ancestry.
… Nature , offer insights into embryonic development, gene regulation and other biological processes vital to … gene expression and how we think about the role of transcription," said co-senior author Susan Celniker, Ph.D., … similarities in genome regulation. Scientists focused on transcription-regulatory factors, key protein regulators that …
The Genomics Landscape
In the August 6, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about NHGRI's completion of the third phase of the ENCODE Project and how it reveals the most extensive catalog to date of candidate functional elements that may regulate the genes in the human and mouse genomes.
… elements, which act as “switches” to regulate gene transcription. The ENCODE findings point to millions of …
Educational Resources
Translation is the process of translating the sequence of a messenger RNA (mRNA) molecule to a sequence of amino acids during protein synthesis.
… to a sequence of amino acids during protein synthesis. … Transcription, Base Pair, Cell, Cytoplasm, Gene, Gene …
Talking Glossary
Methylation is a chemical modification of DNA and other molecules that may be retained as cells divide to make more cells. regulating the production of proteins that the gene encodes.
Staff
Elena Ghanaim is the Policy Advisor for Data Science and Sharing within the Office of Genomic Data Science (OGDS) at the National Human Genome Research Institute (NHGRI)