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- Ethical, Legal and Social Implications (ELSI) Research Program6
- Genomics-Enabled Learning Health Systems (gLHS)2
- Genetic Architecture of Complex Traits1
- Genome Technology Program5
- Human Genome Reference Program (HGRP)2
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Encyclopedia of DNA Elements (ENCODE) Project1
- Molecular Phenotypes of Null Alleles in Cells (MorPhiC)1
- Genomic Innovator Awards2
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)3
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium2
- Developmental Genotype-Tissue Expression (dGTEx)1
- Multi-Omics for Health and Disease (Multi-Omics)1
Talking Glossary
El cáncer es una enfermedad en la que algunas células del cuerpo crecen fuera de control. Hay muchos tipos diferentes de cáncer, y cada uno comienza cuando una única célula adquiere un cambio genómico (o mutación) que le permite dividirse y multiplicarse sin control.
… que le permite dividirse y multiplicarse sin control. … Cancer is a disease in which some of the body’s cells grow uncontrollably. There are many different types of cancer, and each begins when a single cell acquires a genomic change …
News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… NHGRI Communications and Public Liaison Branch … In the largest genomics study of clear cell endometrial cancer (CCEC) tumors to date, National Human Genome Research … senior author and senior investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch . "Because the …
News Release
Researchers are trying to understand a process whose rules are constantly being written and rewritten by cancer's rogue cells: who will more likely relapse.
… Kyle Davis … For a patient with cancer, two of the most important words in the oncologist's lexicon begin with the letter "r": remission and relapse. Many patients will hear the word remission - … associate investigator in the Translational and Functional Genomics Branch at the National Human Genome Research …
News Release
Receiving a cancer diagnosis can feel like losing control of everything.
… Kyle Davis … Receiving a cancer diagnosis can feel like losing control of everything. … In the wake of such a diagnosis, patients, family and friends often yearn for more information. Is it … a senior investigator in the Translational and Functional Genomics Branch at the National Human Genome Research …
Research at NHGRI
The Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch studies the genomic and social determinants of complex diseases.
… The Metabolic, Cardiovascular and Inflammatory Disease Genomics Branch (MCIDGB) studies the genomic and social … advances research into the role of culture, lifestyle, genetics and genomics in disease etiology, differential …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… in tumor DNA that occurs in five different types of cancer. They also found evidence that this methylation … is head of the Genomic Functional Analysis Section and senior investigator in the Translational and Functional Genomics Branch at NHGRI. In 2013, her research group …
News Release
Learn what happens when two genetic neighborhoods merge in brain tumor cells after a gene controlled by a gene-control switch turned on a cancer-growth gene.
… bunny ear loop. These neighborhoods bring distant genes and specific gene control switches into close proximity. … switch from a different genetic neighborhood, turning on a cancer-growth gene. The research team was led by Bradley E. … in energy production, seemed to have no relevance to cancer. Dr. Bernstein and his colleagues found that when the …
News Release
Laura Koehly, Ph.D., has been named chief of NHGRI's Social and Behavioral Research Branch.
… … Laura Koehly, Ph.D., has been named chief of the Social and Behavioral Research Branch (SBRB) in the Intramural … possible in siloed labs. Our research focuses on bringing genomics into health clinics, which will potentially … enterprises. In 1996, she joined the MD Anderson Cancer Center in Houston as a research associate. There, she …
News Release
NIH-funded researchers completed the PanCancer Atlas from over 10,000 tumors representing 33 types of cancer.
… known as the PanCancer Atlas, on a data set of molecular and clinical information from over 10,000 tumors representing 33 types of cancer. … More than 10,000 Tumors Analyzed "This project is … Human Genome Research Institute (NHGRI): NHGRI leads genomics research at the National Institutes of Health (NIH), …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… The Cancer Genome Atlas (TCGA) was a joint effort of the National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI), … targets, similarities to several cancers r  (2014)  As genomics breaches cancer walls, researchers forge new …