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The Genomics Landscape
In the June 2018 issue of The Genomics Landscape, NHGRI Director Eric Green highlights the success of The Cancer Genome Atlas.
… the field of genomics.  …  After more than a decade, The Cancer Genome Atlas (TCGA) program is drawing to an end. A … initiated and supported by NHGRI and the National Cancer Institute (NCI), with over $300 million in total … mission to catalog the genomic changes underlying multiple cancer types. Ambitious in scope from the beginning, TCGA was …
Research Funding
Effort to accelerate understanding of the molecular basis of cancer using genome analysis technologies, including large-scale genome sequencing.
… The Cancer Genome Atlas (TCGA) was a joint effort of the National Cancer Institute (NCI) and the National Human Genome Research …  TCGA study reveals new clues to the genomic diversity of prostate cancers  (2015)  Peering at brain and skin cancers …
News Release
Learn what happens when two genetic neighborhoods merge in brain tumor cells after a gene controlled by a gene-control switch turned on a cancer-growth gene.
… switch from a different genetic neighborhood, turning on a cancer-growth gene. The research team was led by Bradley E. … in energy production, seemed to have no relevance to cancer. Dr. Bernstein and his colleagues found that when the IDH gene was mutated, particular portions of the cancer cells' DNA became studded with chemical tags called …
Staff
Dr. Bell is a senior investigator at the National Human Genome Research Institute's Cancer Genetics and Comparative Genomics Branch.
… She conducted her postdoctoral training at Fox Chase Cancer Center, Philadelphia, before joining Harvard Medical … on the fine-mapping of genomic deletions in ovarian cancer and in malignant mesothelioma as a means to home in on … the dramatic clinical responses of non-small cell lung cancer patients to gefitinib, a small molecule inhibitor of …
Jobs at NHGRI
Postdoctoral positions are available in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the National Human Genome Research Institute, at NIH.
… in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the … to research into the molecular underpinnings of uterine cancer. The overarching goal of the laboratory is to identify … of the most clinically aggressive forms of endometrial cancer. Our research entails the functional annotation of …
Jobs at NHGRI
Postdoctoral positions are available in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the National Human Genome Research Institute, at NIH.
… in the laboratory of Dr. Daphne W. Bell, within the Cancer Genetics and Comparative Genomics Branch of the … to research into the molecular underpinnings of uterine cancer. The overarching goal of the laboratory is to identify … of the most clinically aggressive forms of endometrial cancer. Our research entails the functional annotation of …
Educational Resources
A carcinogen is an agent with the capacity to cause cancer in humans.
… … A carcinogen is an agent with the capacity to cause cancer in humans. … Cancer, Tumor, Genetic Mutation, Chemical … A carcinogen is a substance, organism or agent capable of causing cancer. Carcinogens may occur naturally in the environment …
Educational Resources
An oncogene is a mutated gene that contributes to the development of a cancer.
… is a mutated gene that contributes to the development of a cancer. … Carcinogen, Mutagen, Cancer, Cell, Mutation, Tumor Suppressor Gene … An oncogene is a mutated gene that has the potential to cause cancer. Before an oncogene becomes mutated, it is called a …
News Release
NIH researchers searched for how the body signals the lack of oxygen in melanoma skin cancer.
… the oxygen and nutrients in the original tumor site, the cancer cells travel to other parts of the body (metastasize) … how the body signals the lack of oxygen in melanoma skin cancer, National Institutes of Health (NIH) researchers … acts as a sensor for oxygen and nutrients in many types of cancer. They discovered 40 new genes that are either turned …
Media Availability
Researchers have created a promising new method to accurately and more comprehensively analyze and interpret DNA sequence information from cancer patients.
… analyze and interpret DNA sequence information from cancer patients. They have developed an algorithm that sorts … to their clinical and biological relevance to a patient's cancer. … The findings eventually may help guide … Human Genome Research Institute (NHGRI), and the National Cancer Institute, both part of the National Institutes of …