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- Genome Technology Program2
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Molecular Phenotypes of Null Alleles in Cells (MorPhiC)1
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium1
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News Release
Researchers have now identified three health conditions for which people with SCT are at increased risk.
Educational Resources
Metaphase is a stage during the process of cell division (mitosis or meiosis).
Educational Resources
Proteins are an important class of molecules found in all living cells.
… are an important class of molecules found in all living cells. … Cell, Gene Amplification, Amino Acids, Gene … … in the body. They are critical to most of the work done by cells and are required for the structure, function and … are an important class of molecules found in all living cells. … Educational Resources …
News Release
Researchers find weaker immune response to viral infections in children with mitochondrial disorders
NIH researchers analyzed the gene activities of immune cells in children with mitochondrial disorders and found that their B cells, which produce antibodies to fight viral infections, are less able to survive cellular stress.
… human studies on how mitochondrial function impacts immune cells to guide future treatments. … In a new study, National … Institute (NHGRI), who analyzed gene activity of immune cells in children with mitochondrial disorders and found that B cells, which produce antibodies to fight viral infections, …
Fact Sheets
A knockout mouse is a laboratory mouse in which researchers have inactivated an existing gene by replacing it or disrupting it with an artificial piece of DNA.
… disease.  … Researchers begin by harvesting embryonic stem (ES) cells from early-stage mouse embryos four days after … Mouse, Animal Model, Laboratory Experiment, DNA, Embryonic Stem Cells, Homologous Recombination … A knockout mouse is a …
Educational Resources
Cancer is a group of diseases characterized by uncontrolled cell growth.
… History … Cancer is a disease in which some of the body’s cells grow uncontrollably. There are many different types of …
Educational Resources
Centrioles are paired barrel-shaped organelles located in the cytoplasm of animal cells near the nuclear envelope.
… organelles located in the cytoplasm of animal cells near the nuclear envelope. … Cell Biology, Organelles, … organelles located in the cytoplasm of animal cells near the nuclear envelope. Centrioles play a role in … organelles located in the cytoplasm of animal cells near the nuclear envelope. … Educational Resources …
Educational Resources
Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move.
Health FAQ
Discuss these questions with your doctor or health care provider.
… may have to stop taking it two to three months before the stem cell collection process for gene therapy. You may … These are the general steps:  You will first prepare for stem cell collection.  Two to three months later you will have your stem cells collected.  Your stem cells will take seven to 10 …
Educational Resources
Cytoplasm is the gelatinous liquid that fills the inside of a cell. It is composed of water, salts, and various organic molecules.