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The Genomics Landscape
In the October 2018 edition of The Genomics Landscape, NHGRI Director Dr. Eric Green highlights Dr. Dan Kastner as the Federal Employee of the Year.
… that used positional cloning to identify MEFV, the gene mutated in familial Mediterranean fever (FMF). MEFV … Project Releases First 15 High-Quality Reference Genomes Gene Editing in Dogs Boosts Hope for Kids with Muscular Dystrophy …
Genomics and Medicine
Starting in 2019, the American Journal of Human Genetics has published an annual feature identifying ten key advances in applying genomic information to clinical care that were reported in the previous 12 months of published literature. The Genomic Medicine Working Group has authored these reviews, based on its broader effort to identify notable accomplishments in genomic medicine on a monthly basis. From this larger set of published accomplishments, the working group has continued to select ten papers annually to be highlighted as the most significant.
… may have greater diagnostic utility than a targeted gene panel in sick infants New, specific gene editing may treat sickle cell disease   Read the full review: …
Research Funding
The following are research areas of interest that have been identified by the participating NIH institutes and centers (ICs). Program Officer contact information is also included.
… of results, and mitigating barriers. Research on genome editing for correcting heritable traits and genetic disorders … such as benefit-sharing or equitable access to gene therapies. Genomic sequencing and newborn screening: … constraints, like costs and personnel. Impact of germline gene editing technologies on the consent and autonomy of …
The Genomics Landscape
In the April 2019 edition of The Genomics Landscape, NHGRI Director Eric Green previews the redesigned genome.gov website and its new features.
… Lung, and Blood Institute, who is working to develop a gene therapy-based treatment for sickle cell disease. This … Alcohol Use and Adult Anxiety   Largest-Ever Alzheimer's Gene Study Brings New Answers   Mood-Altering Messenger Goes … Moratorium on Clinical Application of Germline Editing Dr. Collins Discusses NIH's Support for a Moratorium …
The Genomics Landscape
In the May 2024 issue of The Genomics Landscape, NHGRI Director Eric Green talks about the NHGRI Research Training and Career Development Annual Meeting, which provides a venue to foster support and a sense of community for NHGRI-funded trainees, equipping them with tools for success and more clarity about career possibilities.
… with indigenous peoples and the ethics and governance of gene editing. For career development, undergraduates and …
Fact Sheet
A variety of approaches target the blood stem cells to relieve or reduce your symptoms of sickle cell disease.
… It is important to understand the components of gene therapy, how these components differ and other treatment … cells to reduce your symptoms of sickle cell disease.  Gene therapies use your own stem cells, while bone marrow … Types of gene therapy include gene addition and gene editing . There are two types of gene editing: gene silencing …
Archive
Gene-editing technology uncovers genetic link to infertility … …
Professional Development Programs
The Short Course in Genomics offers educators a chance to hear lectures and receive teaching resources from leading researchers, clinicians and staff.
… technologies, brain and behavior, bioinformatics, gene editing, the human microbiome and ethical issues in genomics …
The Genomics Landscape
In the August 6, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about NHGRI's completion of the third phase of the ENCODE Project and how it reveals the most extensive catalog to date of candidate functional elements that may regulate the genes in the human and mouse genomes.
… elements, which act as “switches” to regulate gene transcription. The ENCODE findings point to millions of … bind to DNA, and how RNA molecules interact to regulate gene expression. The results reported in the ENCODE 3 … as polygenic risk scores, behavior, human identity, gene editing, history of eugenics, artificial intelligence, …
National Advisory Council for Human Genome Research
The Director's Report Related documents contain links to materials supplemental to Dr. Eric Green's Director's Report presentation to the National Advisory Council for Human Genome Research in May 2019.
… Human Spaceflight Adopt a Moratorium on Heritable Genome Editing NIH Supports Call for Moratorium on Clinical Uses of Germline Gene Editing 13 Genomes In the News Coast Redwood Walnut … Services Gasperini - A Genome-Wide Framework for Mapping Gene Regulation via Cellular Genetic Screens ENCODE …