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Educational Resources
Cloning is the process of making identical copies of an organism, cell, or DNA sequence.
News Release
A team of NIH-funded researchers have generated the first complete chromosome sequences from non-human primates.
… has only become possible in recent years due to new DNA sequencing technologies and analysis methods. These … X chromosomes. The researchers also used a computational method called alignment, which indicates regions of the …
15 Ways Genomics Influences Our World
Genomics is establishing more robust methods for DNA-based forensic analyses.
… . … As new, more powerful technologies for amplifying and sequencing tiny amounts of DNA became available [see  DNA Sequencing ], scientists teamed up with law enforcement … Advances in genomic technologies, including DNA sequencing, are allowing for more precise identification, in …
The Genomics Landscape
In the October 6, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., celebrates the 25th anniversary of the NIH Intramural Sequencing Center (NISC). a well-respected and highly used large-scale DNA sequencing center that exemplifies the evolution of the field of genomics and the ever-increasing abilities to produce prodigious amounts of genomic data.
… sequence to public databases weekly, as large-scale DNA sequencing had advanced substantially. At that time, it … moved into their first research space in 1997 and began Sanger-based fluorescent DNA-sequencing using six slab … genomic medicine COVID Research NIH-funded team develops method to identify future SARS-CoV-2 mutations that could …
Staff
Dr. Gerard Bouffard directs the Bioinformatics Group at the NIH Intramural Sequencing Center (NISC).
… where he combined his interests in early genome sequencing of the Escherichia coli genome with the nascent … expedited gene discovery on this chromosome, and directed sequencing efforts in the early days of the Human Genome Project. In 1997, he co-founded the NIH Intramural Sequencing Center (NISC) as director of the Bioinformatics …
Media Advisory
The National Institutes of Health (NIH) will host researchers from the Telomere-to-Telomere (T2T) consortium, who have now sequenced the remaining 8% of DNA that was unable to be sequenced by the Human Genome Project and has eluded researchers for nearly two decades.
… What: Virtual press conference to announce T2T consortium sequencing a complete human genome Moderator: Eric Green, …
The Genomics Landscape
In the April 7, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., highlights the Telomere-to-Telomere (T2T) consortium's publishing of a collection of papers that reported the first truly complete sequence of the human genome.
… approach of using the best-available technologies for sequencing DNA and pushing them to their absolute limits. In … filling in the remaining bits because the technologies for sequencing DNA at that time were clearly not up to the task. … Project, more powerful technologies, such as long-read DNA sequencing methods and newer computational tools, aided …
The Genomics Landscape
In the February 12, 2021 edition of The Genomics Landscape, Dr. Eric Green talks about the 20-year anniversary of the publications that reported the draft human genome sequence.
… the 1980s discussing the desirability and feasibility of sequencing the human genome, to the U.S. Department of … Ph.D., former head of sequencing at the Wellcome Trust Sanger Institute, video chatted with NHGRI staff about their … autoinflammatory diseases. … Genomics Research DNA-editing method shows promise to treat mouse model of progeria In …
Clinical Research
This team-based clinical service is provided by NHGRI to Intramural Investigators employing exome/genome sequencing.
… NHGRI to Intramural Investigators employing exome/genome sequencing to accomplish their research goals. The SGFS will … NHGRI to Intramural Investigators employing exome/genome sequencing. ​ … DNA Sequencing, Exam Sequencing, Genome Sequencing, Secondary …
Staff
Dr. James Thomas is the acting director for the NIH Intramural Sequencing Center (NISC).
… Dr. James Thomas is the director of the NIH Intramural Sequencing Center. He oversees the importation and use of DNA sequencing technologies, protocols and analyses, ensuring … that NIH investigators have access to cutting-edge DNA sequencing methods and specialized genomics protocols to meet …