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- Genetic Architecture of Complex Traits1
- Genome Technology Program2
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Molecular Phenotypes of Null Alleles in Cells (MorPhiC)1
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium1
- Developmental Genotype-Tissue Expression (dGTEx)1
Educational Resources
A Golgi body, also known as a Golgi apparatus, is a cell organelle that helps process and package proteins and lipid molecules, especially proteins destined to be exported from the cell.
… Body … A Golgi body, also known as a Golgi apparatus, is a cell organelle that helps process and package proteins and … especially proteins destined to be exported from the cell. … Golgi Apparatus, Camillo Golgi, Cell Biology … A Golgi body, also known as a Golgi apparatus, …
Educational Resources
A fibroblast is the most common type of cell found in connective tissue.
… Fibroblast … A fibroblast is the most common type of cell found in connective tissue. … Cell Biology, Wound Healing … A fibroblast is a type of cell that contributes to the formation of connective tissue, …
Educational Resources
Meiosis is the formation of egg and sperm cells. In sexually reproducing organisms, body cells are diploid, meaning they contain two sets of chromosomes (one set from each parent).
… set from each parent). … Meiosis, Sexually Reproduction, Cell Biology, Chromosome … Meiosis is a type of cell division in sexually reproducing organisms that reduces … a single set of chromosomes. During meiosis, each diploid cell undergoes two rounds of division to yield four haploid …
Educational Resources
Metaphase is a stage during the process of cell division (mitosis or meiosis).
… Metaphase … Metaphase is a stage during the process of cell division (mitosis or meiosis). … Metaphase, Genetic Material, Cell Biology, Chromosome … Metaphase is a stage during the process of cell division (mitosis or meiosis). Normally, individual …
Educational Resources
Proteins are an important class of molecules found in all living cells.
… important class of molecules found in all living cells. … Cell, Gene Amplification, Amino Acids, Gene … Proteins are …
News Release
Researchers find weaker immune response to viral infections in children with mitochondrial disorders
NIH researchers analyzed the gene activities of immune cells in children with mitochondrial disorders and found that their B cells, which produce antibodies to fight viral infections, are less able to survive cellular stress.
… of Health (NIH) researchers found that altered B cell function in children with mitochondrial disorders led to … Mitochondria are important components of nearly every cell in the body because they convert food and oxygen into … the immune system. Using a genomic technique called single-cell RNA sequencing, which analyzes gene activity in …
Media Availability
TCGA researchers have found that chromophobe renal cell carcinoma stems partly from gene alterations in the mitochondria, the cell's energy supplier.
… cancer. … They found that the disease - chromophobe renal cell carcinoma (ChRCC) - stems in part from alterations in genes in the mitochondria, the cell's energy supplier. They also discovered that the tumor … in maintaining telomerase, the enzyme which determines a cell's lifespan. Finally, investigators also found that ChRCC …
Educational Resources
Cancer is a group of diseases characterized by uncontrolled cell growth.
… is a group of diseases characterized by uncontrolled cell growth. … Cancer, Cell Division, Mutation, DNA Error, Metastasis, Tumor, Family … different types of cancer, and each begins when a single cell acquires a genomic change (or mutation) that allows the …
Educational Resources
Centrioles are paired barrel-shaped organelles located in the cytoplasm of animal cells near the nuclear envelope.
… the cytoplasm of animal cells near the nuclear envelope. … Cell Biology, Organelles, Nucleus … Centrioles are paired … play a role in organizing microtubules that serve as the cell's skeletal system. They help determine the locations of the nucleus and other organelles within the cell. … Centrioles are paired barrel-shaped organelles …
Educational Resources
Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move.
… … Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move. … Cell Biology, Proteins, Nucleus … Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move. …