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About Genomics
RNA sequencing and the detection of RNA modifications have recently gained significant attention in the genomics community. New genomic methods and technologies are still needed to advance basic and clinical research into human biology and disease.
… needed to advance basic and clinical research into human biology and disease. … This report - Charting a Future for Sequencing RNA and Its Modifications: A New Era for Biology and Medicine - outlines key focus areas where … needed to advance basic and clinical research into human biology and disease. … RNA sequencing and the detection of …
News Release
NHGRI researchers, collaborators at the University of California (UC) San Diego, UC Davis and the University of Pittsburgh School of Medicine lay out a new framework for comparing dog-to-human aging, one that uses epigenetics as a biological marker to better understand the aging process.
… By comparing when and what epigenetic changes mark certain developmental periods in humans and dogs, researchers hope to … the research. All mammals experience the same overarching developmental timeline: birth, infancy, youth, puberty, … a genetic system for studies that inform human health and biology," said Dr. Ostrander. … Read the study … NHGRI …
Profile
An interview with Meru Sadhu, an Earl Stadtman Investigator and head of the systems biology and genome engineering section within the NHGRI Intramural Research Program, where he talks about his research and why yeast have a special place in his heart.
… Program at NHGRI in 2018. What kind of truth about biology are you most interested in uncovering?  Sadhu: My … being asked to observe and discover the complexities of biology. “That you can get such complex systems starting … is an Earl Stadtman Investigator and head of the systems biology and genome engineering section within the Intramural …
The Genomics Landscape
In the August 6, 2020 edition of The Genomics Landscape, Dr. Eric Green talks about NHGRI's completion of the third phase of the ENCODE Project and how it reveals the most extensive catalog to date of candidate functional elements that may regulate the genes in the human and mouse genomes.
… (NICHD) are collaborating to support a new initiative, the Developmental Genotype-Tissue Expression ( dGTEx ) Project. … Laboratory, Data Analysis, and Coordinating Center for the Developmental Genotype-Tissue Expression Project Pediatric … Biospecimen Procurement Center (BPC) supporting the Developmental Gene Expression (dGTEx) Project Ruth L. …
Educational Resources
A nuclear membrane is a double membrane that encloses the cell nucleus.
… the cell nucleus. … Nuclear Membrane, Chromosome, Cell Biology … The nuclear membrane is a double layer that …
Educational Resources
DNA replication is the process by which a molecule of DNA is duplicated.
… molecule of DNA is duplicated. … DNA, Cell Division, Cell Biology … DNA replication is the process by which the …
Educational Resources
Cytoplasm is the gelatinous liquid that fills the inside of a cell. It is composed of water, salts, and various organic molecules.
… molecules. … Organelles, Mitochondria, Nucleus, Cell Biology … Cytoplasm is the gelatinous liquid that fills the …
Educational Resources
A centrosome is a cellular structure involved in the process of cell division.
… in the process of cell division. … Cell Division, Basic Biology, Nucleus … A centrosome is a cellular structure …
Fact Sheets
A transcriptome is a collection of all the gene readouts present in a cell.
… and rat are important models with which to study human biology. The Mouse Transcriptome Project was an NIH-supported … transcriptome. Both Novartis and the European Molecular Biology Laboratory have well-established gene expression … readouts present in a cell. … Transcriptome, Genes, Cell Biology, RNA Sequence, DNA … A transcriptome is a collection …
Educational Resources
Meiosis is the formation of egg and sperm cells. In sexually reproducing organisms, body cells are diploid, meaning they contain two sets of chromosomes (one set from each parent).
… from each parent). … Meiosis, Sexually Reproduction, Cell Biology, Chromosome … Meiosis is a type of cell division in …