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An anticodon is a trinucleotide sequence complementary to that of a corresponding codon in a messenger RNA (mRNA) sequence.
… a unit of genetic information encoding a particular amino acid. An anticodon is a trinucleotide sequence located at one … in a messenger RNA (mRNA) sequence. Each time an amino acid is added to a growing polypeptide during protein … on the mRNA molecule, ensuring that the appropriate amino acid is inserted into the polypeptide. … An anticodon is a …
Research Funding
CSER is rapidly advancing the knowledge necessary to develop best practices for implementating genomic sequence data into clinical care.
… Reports of genomic sequencing being applied to the medical care of individual … most likely to be usefully addressed by a genomic sequencing approach still accumulating. Incorporation of … co-funding from NCI, subsequently crafted the Clinical Sequencing Exploratory Research (CSER) initiative to: 1) …
Educational Resources
An intron is a portion of a gene that does not code for amino acids.
… that does not code for amino acids. … Intron, Exon, Amino Acid, DNA Sequence, Gene … An intron is a region that resides …
Staff
Dr. Gerard Bouffard directs the Bioinformatics Group at the NIH Intramural Sequencing Center (NISC).
… where he combined his interests in early genome sequencing of the Escherichia coli genome with the nascent … sequencing of cDNA clones using the transposon Tn5. Nucleic Acids Res , 30(11):2469-77. 2002. [ PubMed ] Wistow … and genome portal for hematology and erythroid biology. Nucleic Acids Res , 1;32(Database issue):D572-4. 2004. [ …
News Release
NIH researchers have developed and released an innovative software tool, called Verso, to assemble truly complete (i.e., gapless) genome sequences from a variety of species. The software makes the process of assembling complete genome sequences more affordable and accessible.
… complete genome sequence.” The T2T consortium used new DNA sequencing technologies and analytical methods to generate … like putting together a jigsaw puzzle, and different DNA sequencing technologies generate different types of genomic … researchers tested Verkko with human and non-human genome sequencing data. The software quickly and precisely assembled …
Educational Resources
A contig is a series of overlapping DNA sequences used to make a map that reconstructs the original DNA sequence of a chromosome or a region of a chromosome.
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… biology of living things have changed over time. As DNA sequencing technology becomes more powerful and less … both plants and animals, consist of DNA (deoxyribonucleic acid), the chemical chain that includes the genes that code … list continues to grow almost daily. In addition to the sequencing of the human genome, which was completed in 2003, …
News Release
NHGRI has selected James Thomas, Ph.D., as the new director of the NIH Intramural Sequencing Center (NISC), to will oversee the importation and use of DNA sequencing technologies, protocols and analyses, ensuring that NIH investigators have access to cutting-edge DNA sequencing methods and specialized genomics protocols to meet their research needs.
… Thomas, Ph.D. , as the new director of the NIH Intramural Sequencing Center (NISC). In this role, Dr. Thomas will oversee the importation and use of DNA sequencing technologies, protocols and analyses, ensuring … that NIH investigators have access to cutting-edge DNA sequencing methods and specialized genomics protocols to meet …
Profile
Jim Mullikin pioneered DNA sequencing technologies during the Human Genome Project and other major advances in genomics.
… Mullikin pioneered DNA sequencing technologies during the Human Genome Project and … the whole progress, from the very early days of Sanger sequencing all the way to a complete telomere-to-telomere … NISC has evolved in tandem with rapidly advancing DNA sequencing technologies. When I was appointed acting director …
Educational Resources
Polymorphism involves one of two or more variants of a particular DNA sequence.
… a particular DNA sequence. … Base Pair, Deoxyribonucleic Acid (DNA), Genotype, Mutation, Phenotype … Polymorphism, as …