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The Advances in Genomic Technology Development (AGTD) 2023 Annual Meeting was hosted by the Technology Development Coordinating Center (TDCC) in-person and virtually from Tuesday, June 6, until Thursday, June 8, at The Sanford Consortium for Regenerative Medicine, La Jolla, CA.
… Salk Institute for Biological Studies 8:45 a.m. STAMPing RNA binding protein-RNA networks Gene Yeo, Ph.D., MBA University of California, … Update: Programmable Eukaryotic Protein Expression with RNA Sensors Omar Abudayyeh, Ph.D. Massachusetts Institute of …
Event
The Advances in Genomic Technology Development (AGTD) 2022 Annual Meeting was hosted by the Technology Development Coordinating Center (TDCC) from July 12-14, 2022 at The Jackson Laboratory (Farmington, CT).
… Update: Programmable Eukaryotic Protein Expression with RNA Sensors Omar Abudayyeh, Ph.D. Massachusetts Institute of … of Washington 1:30 p.m. A Novel Approach for Studying RBP-RNA and RBP-RBP Interactions at Isoform and Single-Molecule … Dinner  Wednesday, July 13, 2022  Time Topic Speaker RNA Sequencing: Part I Session Moderators: Xiaoxu Li, Ph.D., …
Fact Sheet
Early in the COVID-19 pandemic, researchers used state-of-the-art genomic sequencers to quickly sequence the SARS-CoV-2 virus.
… First, they separate the two strands of plasmid DNA. Then, RNA polymerase, the molecule that transcribes RNA from DNA, uses the spike protein gene to create a single …
Research Funding
A list of current and previous Centers of Excellence in Genomic Science (CEGS) grant awards.
… silencing or activation of messenger RNAs, long noncoding RNA and a host of other regulatory elements such as enhancers … neurodevelopmental disease and cancer. Center for Dynamic RNA Epitranscriptomes RM1 HG008935 Chuan He University of Chicago Chemical modifications on mammalian messenger RNA (mRNA) have recently been shown to play critical and …
Fact Sheet
Genomic research has been central to understanding and combating the SARS-CoV-2 (COVID-19) pandemic.
… virus, which is the pathogen that causes COVID-19, uses RNA as its genetic material. First, the PCR is converted from single-stranded RNA to double-stranded DNA in a process called reverse … of DNA copies corresponding to the SARS-CoV-2 viral RNA. … What do results mean for a COVID-19 PCR test?  A …
Staff
Dr. Daniel Gilchrist is a program director of Computational Genomics and Data Science in NHGRI's Division of Genome Science.
… GW, Burkholder A, Fargo DC, Adelman K. Stable pausing by RNA polymerase II provides an opportunity to target and … G, Fargo DC, Xie B, Gao Y, Li L, Adelman K. Pausing of RNA polymerase II disrupts DNA-specified nucleosome … S, Shah R, Parker JS, Grissom SF, Zeitlinger J, Adelman K. RNA polymerase is poised for activation across the genome. …
Policy Issues
Scientists have edited genomes for many years, but CRISPR technology has improved the speed, cost, accuracy, and efficiency of genome editing
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… in the lab. 4 With CRISPR, researchers create a short RNA  template that matches a target DNA sequence in the genome. Creating synthetic RNA sequences is much easier than engineering proteins as is those required for ZFNs and TALENs. Strands of RNA and DNA can bind to each other when they have matching …
About Genomics
In 2003, an accurate and complete human genome sequence was finished two years ahead of schedule and at a cost less than the original estimated budget.
… DNA, a synthetic type of DNA generated from messenger RNA, or mRNA, the molecule in the cell that takes information … how large numbers of genes are expressed as messenger RNA in a particular tissue, and how a cell's regulatory … the structural components, or building blocks, of DNA and RNA. A nucleotide consists of a base chemical - either …
News Release
Six new grants will support researchers for new computational approaches to search millions of genomic variants for disease susceptibility.
… not translated into proteins, they may be transcribed into RNA. Such RNA carries out various regulatory functions in a cell. The researchers have shown that disrupting RNA structure can lead to diseases in people, including an …
Diversity Center
The Morehouse School of Medicine established the Center of Genomic Diversity that aims to create a transformative impact on genomics research and health outcomes in minority populations, fostering an inclusive and equitable research environment.
… the differential metrics of short and long read RNA seq data aligned to the GRCh38 reference genome and the … to further improve quality of short and long read RNA seq alignments, compared to the GRCh38 reference genome, … genomes. Measure the QC metrics of short and long -read RNA seq data aligned to the GRCh38 reference genome compared …