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- Impact of Genomic Variation on Function (IGVF) Consortium1
- Encyclopedia of DNA Elements (ENCODE) Project1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium1
- Multi-Omics for Health and Disease (Multi-Omics)1
- Ethical, Legal and Social Implications (ELSI) Research Program4
- Genomics-Enabled Learning Health Systems (gLHS)1
The Genomics Landscape
In the November 2018 edition of The Genomics Landscape, NHGRI Director Eric Green highlights the 25th anniversary of NHGRI's Intramural Research Program.
… disease genes, including those implicated in cancer, diabetes, premature aging, hereditary deafness, and various … Map of the Genome Gene Mutation Points to New Way to Fight Diabetes, Obesity, Heart Disease Study Identifies Gene that …
Staff
Jie Zhou is a data manager and SAS programmer at NHGRI's Center for Research on Genomics and Global Health.
… in African Americans. J Endocrinol Metab. 2012 Apr 1;2(2):51-65. Chen G, Yuan A, Zhou Y, Bentley AR, Zhou J, Chen … with obesity in West Africans and African Americans. Diabetes. 2010 Jun;59(6):1549-54. doi: 10.2337/db09- 1252. … Rotimi C. Genome-wide search for susceptibility genes to type 2 diabetes in West Africans: potential role of …
Event
The Genomics and Health Disparities Lecture Series was formed to enhance opportunities for dialogue about how innovations in genomics research and technology can impact health disparities. Topics will range from basic science to translational research.
… Heart, Lung and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases and the National …
Staff
Dr. Charles Rotimi is the scientific director of and NIH Distinguished Investigator in the Division of Intramural Research. He also serves as the director of the Center for Research on Genomics and Global Health (CRGGH).
… and blood pressure in African Americans and for type-2 diabetes in West Africans. His lab contributes to the global …
Educational Resources
A complex disease is caused by the interaction of multiple genes and environmental factors.
… of complex genetic diseases include heart disease, diabetes, and cancer. … A complex disease is caused by the …
Staff
Dr. Ayo Doumatey is a Research Fellow and Laboratory Manager at NHGRI's Center for Research on Genomics and Global Health.
… Adeyemo AA, Tekola-Ayele F, Doumatey AP, et al. Impact of Type 2 Diabetes on Impaired Kidney Function in Sub-Saharan African …
Talking Glossary
Una enfermedad (o afección) compleja, cuando se analiza en el contexto de la genética, refleja un trastorno que se produce por las contribuciones de múltiples variantes genómicas y genes además de influencias considerables del entorno fÃsico y social.
… of complex genetic diseases include heart disease, diabetes, and cancer. … Una enfermedad (o afección) compleja, …
Research Funding
The Multi-Omics for Health and Disease Consortium aims to advance the application of multi-omic technologies to study health and disease in ancestrally diverse populations.
… Chicago Multi-Omics at the Intersections of Environment, Diabetes, and Kidney Disease: A Multi-Omics for Health and … include 1) persons from ancestrally diverse populations; 2) persons with and without specific diseases; 3) harmonized …
News Release
Researchers build a statistical model using family health history to improve disease risk assessment
Researchers at the National Human Genome Research Institute (NHGRI) have developed a new statistical model that can predict the risk for developing diseases by combining information about family member health and lifestyle factors from family members.
… health and require further testing. The researchers used type 2 diabetes mellitus (T2D) as the disease model for their study. …
News Release
NHGRI hosted two Pathway to Independance awardees and supported 18 additional investigators at institutions nationwide.
… Ph.D., received his award from the National Institute of Diabetes and Digestive and Kidney Disorders, enabling him to … in the non-coding portion of the genome, with a focus on Type 2 diabetes. He is looking forward to integrating his twin …