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News Release
A the largest genomics study of clear cell endometrial cancer (CCEC) tumors has identified mutations in the TAF1 gene.
… been previously implicated in CCEC. TAF1 encodes part of a transcription factor complex, which regulates the expression …
Staff
Dr. Paul Meltzer is an adjunct investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
News Release
NIH researchers searched for how the body signals the lack of oxygen in melanoma skin cancer.
… and her team will analyze the roles that HIF1α and other transcription factors play in turning genes on and off in …
About Genomics
Resources for understanding the first complete, gapless sequence of a human genome.
Staff
Dr. Settara Chandrasekharappa is an associate investigator in NHGRI's Cancer Genetics and Comparative Genomics Branch.
… interaction with several different proteins, including the transcription factor JunD, and its requirement in endodermal …
Educational Resources
Gene expression is the process by which the information encoded in a gene is used to direct the assembly of a protein molecule.
… gene is turned into a function. This mostly occurs via the transcription of RNA molecules that code for proteins or …
Staff
Dr. Sharon Milgram is an adjunct investigator in the Genetics and Molecular Biology Branch at the National Human Genome Research Institute.
… and regulates its co-activation of p73-mediated Bax transcription. J Biol Chem , 279:26300-26306. 2004. [ PubMed …
Event
NHGRI and the University at Buffalo Center for Disability Studies will hold a two-day symposium on October 6-7, 2022 to address historical constructions of disability and ableism, with a focus on the “irreducibility” of individuals with disability and the history of disability.
Staff
Dr. Charles Venditti is a chief and senior investigator of NHGRI's Metabolic Medicine Branch.