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News Release
The National Academy of Medicine elected Dr. Charles Rotimi, CRGGH Director, as one of its new members.
… were described as follows: For groundbreaking research in African and African ancestry populations, providing new insights into the genetic …
News Release
A new phase of the IGNITE Network will conduct clinical trials of genomic medicine interventions.
… and all three conditions are more common among people of African ancestry than European and Asian descent. Specific African populations have two common mutations in the …
News Release
NHGRI researchers and colleagues are calling for health disparities research that focuses on the microbiome.
… cultural and behavioral factors in people of diverse ancestry, according to the perspective. "We hope that … influence in health disparities can be found among some African American woman, according to the perspective. Research has shown that differences in some African American women's vaginal microbiome may result in …
The Genomics Landscape
In the November 3, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the important genomics legacy of the Human Heredity and Health in Africa (H3Africa) program as it comes to an end.
… with the aim of developing a sustainable and collaborative African genomics research enterprise. With most of its … and the UK Wellcome Trust (in strong partnership with the African Society for Human Genetics ), H3Africa has fostered … from K. Sean Kimbro, Ph.D. , about health disparities and ancestry-driven drug discovery. This month will feature …
Staff
Jie Zhou is a data manager and SAS programmer at NHGRI's Center for Research on Genomics and Global Health.
… Zhou J, McLeod H, Adeyemo A, Rotimi CN. Pharmacogenomics, ancestry and clinical decision making for global populations. … variants with ethnicity-specific effects in African Americans. PLoS Genet. 2014 Mar 6;10(3):e1004190. … new loci associated with body mass index in individuals of African ancestry. Nat Genet. 2013 Jun;45(6):690-6. doi: …
Research at NHGRI
A list of publications led by or in collaboration with the Center for Research on Genomics and Global Health.
… polygenic prediction for kidney function in persons with ancestry from Africa and the Americas. Cell Genom . … of community gatekeepers about genomic risk information in African cleft research. BMC Public Health . 24(1):507. 2024. … risk between major orofacial cleft phenotypes in an African population. Genet Epidemiol . 2024. [ PubMed ]  Zhu …
Profile
Dr. Hanchard talks about his journey into genetics research, his collaborations with international researchers, and the importance of determination in science.
… the genomics and environmental contributors of diseases in African populations. Diversifying genomics research is at the … Dr. Hanchard studies are more common in individuals of African ancestry. In fact, diversity is at the core of his research …
Staff
Dr. Daniel Shriner is a researcher in NHGRI's Center for Research on Genomics and Global Health.
… and association with obesity in West Africans and African-Americans. Diabetes 59(6):1549–1554. PMCID: … 2010. Genome wide association of anthropometric traits in African and African derived populations. Hum. Mol. Genet. … association for renal traits among participants of African ancestry reveals new loci for renal function. PLoS Genet ., …
Fact Sheet
Pharmacogenomics is a growing area of genomic medicine that uses a person’s genomic information to help healthcare providers select the medications and dosages that are predicted to work best in each patient.
… Center, omitting the name for privacy reasons.  “I am an African American woman in my 30s and was recently diagnosed … on data obtained from people with predominantly European ancestry. This means that pharmacogenomic tests may miss …
The Genomics Landscape
In the August 2023 edition of The Genomics Landscape, NHGRI Director Eric Green introduces incoming NHGRI DEO Director, Jennifer Troyer.
…  … Polygenic scoring accuracy varies across the genetic ancestry continuum Ding et al. Nature . 2023 … that involve data generated from individuals of European ancestry, but such studies are limited in their applicability … training, and ethical guidelines to support sustainable African research. Dr. Troyer also co-managed the …