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- Genome Technology Program2
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Molecular Phenotypes of Null Alleles in Cells (MorPhiC)1
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium1
- Developmental Genotype-Tissue Expression (dGTEx)1
Talking Glossary
A gamete is a reproductive cell of an animal or plant.
… or plant. In animals, female gametes are called ova or egg cells, and male gametes are called sperm. Ova and sperm are haploid cells, with each cell carrying only one copy of each …
Educational Resources
Bacteria are small single-celled organisms.
… and in fact is estimated to contain more bacterial cells than human cells. Most bacteria in the body are harmless, and some are …
Talking Glossary
Methylation is a chemical modification of DNA and other molecules that may be retained as cells divide to make more cells. regulating the production of proteins that the gene encodes.
… of DNA and other molecules that may be retained as cells divide to make more cells. … Methylation is a chemical modification of DNA and other molecules that may be retained as cells divide to make more cells. When found in DNA, …
The Genomics Landscape
In the July 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the legacy the LINCS program leaves as it has completed its goal of creating a large-scale, systematically generated molecular and cellular dataset.
… and cellular dataset to help scientists understand how cells respond to specific biological and environmental … LINCS program generated dataset to help understand how cells functio … NHGRI and NCI award $33 million to improve … LINCS program generated dataset to help understand how cells function … In the July 2021 issue of The Genomics …
Fact Sheets
Chromosomes are thread-like structures located inside the nucleus of animal and plant cells.
… structures located inside the nucleus of animal and plant cells. … Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single … packaging, DNA molecules would be too long to fit inside cells. For example, if all of the DNA molecules in a single …
Educational Resources
Haploid is the quality of a cell or organism having a single set of chromosomes.
… presence of a single set of chromosomes in an organism’s cells. Sexually reproducing organisms are diploid (having two … one from each parent). In humans, only the egg and sperm cells are haploid. … Haploid is the quality of a cell or …
Educational Resources
Monosomy refers to the condition in which only one chromosome from a pair is present in cells rather than the two copies usually found in diploid cells.
… pair instead of the usual two copies found in diploid cells. … Monosomy, Chromosome, Diploid, Genetic Diseasem, … in which only one chromosome from a pair is present in cells rather than the two copies usually found in diploid cells. When cells have one chromosome from a pair plus a …
Educational Resources
The instructions in a gene that tell the cell how to make a specific protein.
Fact Sheet
Ribonucleic acid (RNA) is an essential molecule that performs many roles in the cell, from carrying the instructions to make proteins to regulating genes.
… have already identified over 150,000 unique mRNAs in human cells, which is over seven times the number of genes in the … a protein) that is found in a virus. When the mRNAs enter cells in the body, the cells use the mRNAs to produce virus proteins and display …