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The Genomics Landscape
In April 6, 2023 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., talks about how NHGRI will hold a symposium on National DNA Day, April 25, highlighting relevant and interesting topics in genomics and concluding with the annual Louise M. Slaughter National DNA Day Lecture.
… sampled over 300 dogs to characterize their genetic ancestry and found large, complex families of dogs living in …
Staff
Dr. Amy Bentley is a Staff Scientist with the NHGRI's Center for Research on Genomics and Global Health.
… traits, particularly serum lipids, in African ancestry populations. She also focuses on the complex … consortium, in order to support the inclusion of African ancestry populations in such efforts. Dr. Bentley is very … A, Rotimi CN. Phenotypic variance explained by local ancestry in admixed African Americans. Front Genet , 2015 …
Event
On October 25-29, 2022, the National Human Genome Research Institute (NHGRI) will participate in the ASHG Annual Meeting - the world's largest human genetics and genomics meeting and exposition.
… Traits Quantification of race, ethnicity, and genetic ancestry disparities in anti-hypertensive drug efficacy in … Research Quantification of race, ethnicity, and genetic ancestry disparities in anti-hypertensive drug efficacy in … p.m. Statistical Genetics and Genetic Epidemiology Local Ancestry at the MHC region id asscociated with disease …
DIversity Center
Florida International University establishes a Diversity Center for Genome Research.
… historically been biased toward populations of European ancestry, leading to a lack of representation and … and prognosis in minority populations. We propose Allelic Ancestry Specific PRS (aPRS), which generates accurate allelic ancestry-specific summary statistics, addressing limitations …
Research Funding
ClinGen will advance genomics in clinical care and improve our understanding of phenotypic and functional effects of genetic variants and their clinical value.
… efforts in the establishment of standards in the use of ancestry and diversity information in clinical genomics and … could be prevented or mitigated if the risk were known Ancestry and Diversity Alice Popejoy Carlos Bustamante Investigate how ancestry information is used in clinical genomics and provide …
Event
Several NIH Institutes, Offices and Centers partnered to host a two-day virtual workshop on May 28-29, 2024, to further explore the recommendations from the National Academies of Sciences, Engineering and Medicine (NASEM) 2023 report, Using Population Descriptors in Genetics and Genomics Research: A New Framework for an Evolving Field, with regards to legacy genomic data. 
News Release
A new phase of the IGNITE Network will conduct clinical trials of genomic medicine interventions.
… three conditions are more common among people of African ancestry than European and Asian descent. Specific African … to diverse clinical care settings. “Patients of African ancestry might experience better management of high blood …
Health
A polygenic risk score is one way by which people can learn what their risk of developing a disease is, based on the total number of genomics variants related to the disease.
… studies to date have examined individuals of European ancestry. Because of this issue, there may not be adequate … beyond polygenic risk scores. The percentage  of ancestry populations included in large-scale genomic studies … risk scores may only be valid and useful for European ancestry populations. More research is needed to derive the …
Research Funding
The three research domains to be considered for support by the NHGRI Ethical, Legal and Social Implications Research Program.
… social inequities. How concepts of race, ethnicity and ancestry have been (and are currently) used in genomic … genomics on the conceptualization of race, ethnicity and ancestry across diverse individuals and groups. How genomic … direct-to-consumer (DTC) companies that offer genetic ancestry testing and other genomic services, law enforcement, …
News Release
NIH-led study finds genetic markers that explain up to 12% of the differences between two people’s blood pressure.
… the collected data was mostly from people of European ancestry (due to limited availability of diverse datasets … risk scores were also applicable to people of African ancestry, which was confirmed through analyzing data from …