Search Results
Facet (Page)
Refine Your Search
Audiences
Content Formats
Events
Sections
Divisions
Staff
Dr. Heidi Sofia served as a program director in the Division of Genomic Medicine at the National Human Genome Research Institute from 2010-2023.
… NHGRI in 2010 as part of the team responsible for The Cancer Genome Atlas (TCGA) initiative in cancer genomics, jointly managed by NHGRI and the National Cancer Institute (NCI). TCGA was instrumental in setting the …
Fact Sheets
Epigenomics is a field in which researchers chart the locations and understand the functions of all the chemical tags that mark the genome.
… associated with body overgrowth and increased risk of cancer; Prader-Willi syndrome, associated with poor muscle … changes can lead to uncontrolled growth, a hallmark of cancer, or to a failure of the immune system to destroy … have had some success in treating patients with the drug temozolomide, which kills cancer cells by adding methyl …
Educational Resources
A tumor suppressor gene directs the production of a protein that is part of the system that regulates cell division.
… the system that regulates cell division. … BRCA1, BRCA2, Cancer, Oncogene, Cell, Gene, Mutation … A tumor suppressor … Such mutations may contribute to the development of a cancer. … A tumor suppressor gene directs the production of a …
Educational Resources
A complex disease is caused by the interaction of multiple genes and environmental factors.
… of multiple genes and environmental factors. … Genes, Cancer, Heart Disease, Gene-environment Interactions … A … genetic diseases include heart disease, diabetes, and cancer. … A complex disease is caused by the interaction of …
Educational Resources
A mutagen is a chemical or physical phenomenon, such as ionizing radiation, that promotes errors in DNA replication.
… DNA replication. … Mutagen, DNA Mutation, DNA Replication, Cancer … A mutagen is a chemical or physical agent capable of …
Educational Resources
Gene amplification is an increase in the number of copies of a gene sequence.
… the number of copies of a gene sequence. … DNA Sequence, Cancer, PCR, Polymerase Chain Reaction, Laboratory Experiment … an increase in the number of copies of a gene in a genome. Cancer cells, for example, sometimes produce multiple copies …
News Release
NHGRI researchers have identified a genomic signature for some aggressive prostate tumors, which may help healthcare providers pinpoint treatment options.
… challenge health care providers face in treating prostate cancer is distinguishing the aggressive, potentially … way to identify a specific subgroup of prostate cancer tumors with a known treatment option," said Elaine … the study's corresponding author and chief of NHGRI's Cancer Genetics and Comparative Genomics Branch . "New …
Educational Resources
Apoptosis is the process of programmed cell death.
… death. … Programmed Cell Death, Development, DNA Repair, Cancer, Tumor, Cell Division … Apoptosis is the process of … beyond repair. Apoptosis also plays a role in preventing cancer. If apoptosis is for some reason prevented, it can …
Event
NHGRI, National Institute of Environmental Health Sciences (NIEHS) and National Cancer Institute (NCI) will host a pre-application interactive webinar for the Multi-Omics for Health and Disease program funding opportunity announcements (FOAs): RFA-HG-22-008,
RFA-HG-22-009 and RFA-HG-22-010.
… of Environmental Health Sciences (NIEHS) and National Cancer Institute (NCI) will host a pre-application … of Environmental Health Sciences (NIEHS) and National Cancer Institute (NCI) will host a pre-application … of Environmental Health Sciences (NIEHS) and National Cancer Institute (NCI) will host a pre-application …
Educational Resources
Gene therapy is an experimental technique for treating disease by altering the patient's genetic material.
… … Genetic Disease, Genetic Disorder, Gene Mutation, Cancer Treatment, Healthcare … Gene therapy is a technique …