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- Genome Technology Program2
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Molecular Phenotypes of Null Alleles in Cells (MorPhiC)1
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)1
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium1
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The Genomics Landscape
In the July 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the legacy the LINCS program leaves as it has completed its goal of creating a large-scale, systematically generated molecular and cellular dataset.
… agents and their effects on the development of a cell’s normal state. In addition, LINCS developed a resource … “signatures” that reflect the responses that different cell types show under different conditions. LINCS was based … cellular characteristics, behavior, and/or function of a cell. In the past, most research studies designed to …
Educational Resources
The genome is the entire set of genetic instructions found in a cell.
… is the entire set of genetic instructions found in a cell. … Genome, Genomics, DNA Sequence, Human Genome Project, … genome is the entire set of DNA instructions found in a cell. In humans, the genome consists of 23 pairs of chromosomes located in the cell’s nucleus, as well as a small chromosome in the cell’s …
Fact Sheets
Chromosomes are thread-like structures located inside the nucleus of animal and plant cells.
… Scientists gave this name to chromosomes because they are cell structures, or bodies, that are strongly stained by some … For example, if all of the DNA molecules in a single human cell were unwound from their histones and placed end-to-end, … produce new cells to replace old, worn-out cells. During cell division, it is essential that DNA remains intact and …
Educational Resources
Haploid is the quality of a cell or organism having a single set of chromosomes.
… Haploid … Haploid is the quality of a cell or organism having a single set of chromosomes. … … and sperm cells are haploid. … Haploid is the quality of a cell or organism having a single set of chromosomes. … …
Educational Resources
Monosomy refers to the condition in which only one chromosome from a pair is present in cells rather than the two copies usually found in diploid cells.
Educational Resources
The instructions in a gene that tell the cell how to make a specific protein.
… Genetic Code … The instructions in a gene that tell the cell how to make a specific protein. … ACGT, Base Pairs, … refers to the instructions contained in a gene that tell a cell how to make a specific protein. Each gene’s code uses … a protein. … The instructions in a gene that tell the cell how to make a specific protein. … Educational Resources …
Fact Sheet
Ribonucleic acid (RNA) is an essential molecule that performs many roles in the cell, from carrying the instructions to make proteins to regulating genes.
… DNA, and this information helps the RNA do its job in the cell. This process, where a gene produces RNA molecules, … transcribed from genes in the nucleus , the part of the cell that contains the genome. The mRNAs then travel out of … tail . When scientists want to study only the mRNAs in a cell, they use special tools to select only the RNAs that …
For Teachers
A microbiome is all of the genetic material found in a microbe, such as a bacterium, fungal cell or virus.
… material found in a microbe, such as a bacterium, fungal cell or virus. It also may refer to the genetic material … material found in a microbe, such as a bacterium, fungal cell or virus. … Microbiome, Microbes, Genetic Material, … material found in a microbe, such as a bacterium, fungal cell or virus. … For Teachers …
Educational Resources
A cytogeneticist is a geneticist who specializes in the study of chromosomes and the structure and function of the cell.
… study of chromosomes and the structure and function of the cell. … Chromosomes, Microscopy, Careers … A cytogeneticist … study of chromosomes and the structure and function of the cell. … A cytogeneticist is a geneticist who specializes in … study of chromosomes and the structure and function of the cell. … Educational Resources …
Educational Resources
Cytogenetics is the branch of genetics that studies the structure of DNA within the cell nucleus.
… of genetics that studies the structure of DNA within the cell nucleus. … DNA, Nucleus, Chromosomes, Fluorescence In … containing DNA that reside within the nucleus of a cell. During cell division, these structures become condensed and are …