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News Release
NIH will renew three awards totaling $73.2 million over five years to continue building the Clinical Genome (ClinGen) resource, an effort to collect and archive information about clinically relevant genes and genomic variants for use in precision medicine.
… collect and archive information about clinically relevant genes and genomic variants for use in precision medicine. The … lack of organized availability of information about which genes and genomic variants are relevant to human disease. … to fill that gap. The consortium works to identify which genes are associated with disease and which variants in those …
News Release
CRGGH researchers Amy Bentley and Charles Rotimi have just completed a large-scale, multi-ancestry genome-wide analysis of gene × smoking interactions on the concentration of serum lipids, including high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), and triglycerides.
Educational Resources
Positional cloning is a laboratory technique used to locate the position of a disease-associated gene along the chromosome.
Clinical Research
The CLINSEQ® Study seeks to learn about the role that your genes play in your health.
… The CLINSEQ® Study seeks to learn about the role that your genes play in your health. We do this by getting a DNA sample from you, sequencing most or all of your genes, and comparing that to what we know about your personal and family health histories. We look at genes related to a variety of conditions, including heart …
Educational Resources
The instructions in a gene that tell the cell how to make a specific protein.
… cell how to make a specific protein. … ACGT, Base Pairs, Genes, DNA, Double Helix, Adenine, Cytosine, Guanine, Thymine …
Educational Resources
Recessive Traits and Alleles is a quality found in the relationship between two versions of a gene.
Fact Sheet
A variety of approaches target the blood stem cells to relieve or reduce your symptoms of sickle cell disease.
… , your stem cells are changed by altering part of your genes. Types of gene therapy include gene addition and gene … are present at the time of the gene therapy nor alter the genes that you pass on to your children. … Bone marrow … your stem cells are replaced with new stem cells that have genes that do not code for sickle cell disease. These new …
Educational Resources
Duplication is a type of mutation that involves the production of one or more copies of a gene or region of a chromosome.
… a gene or region of a chromosome. … Mutation, Chromosome, Genes, Evolution … Duplication, as related to genomics, …
Educational Resources
A polygenic trait is one whose phenotype is influenced by more than one gene.
… as height or skin color, that is influenced by two or more genes. Because multiple genes are involved, polygenic traits do not follow the …