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Educational Resources
A physical map of a chromosome or a genome that shows the physical locations of genes and other DNA sequences of interest.
… that shows the physical locations of genes and other DNA sequences of interest. … Chromosome, Gene, Deoxyribonucleic Acid (DNA), Positional Cloning … A physical map, as related to … of landmarks or markers (such as genes, variants and other DNA sequences of interest) within a chromosome or genome. A …
Educational Resources
A locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address.
… locus is the specific physical location of a gene or other DNA sequence on a chromosome, like a genetic street address. … Locus, Allele, DNA Polymorphism, Gene, Chromosome … A locus, as related to … or location within a genome (such as a gene or another DNA segment of interest), somewhat like a street address. The …
Policy Issues
Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals.
… Genome editing is a method that lets scientists change the DNA of many organisms, including plants, bacteria, and animals. Editing DNA can lead to changes in physical traits, like eye color, … editing technologies enable scientists to make changes to DNA, leading to changes in physical traits, like eye color, …
Educational Resources
A primer is a short, single-stranded DNA sequence used in the polymerase chain reaction (PCR) technique.
… Primer … A primer is a short, single-stranded DNA sequence used in the polymerase chain reaction (PCR) technique. … Deoxyribonucleic Acid (DNA), Gene Amplification, Hybridization, Polymerase Chain … primer, as related to genomics, is a short single-stranded DNA fragment used in certain laboratory techniques, such as …
Educational Resources
A marker is a DNA sequence with a known physical location on a chromosome. Markers can help link an inherited disease with the responsible genes.
… Marker … A marker is a DNA sequence with a known physical location on a chromosome. … an inherited disease with the responsible genes. … Marker, DNA Sequence, Gene, Inheritance … A marker (largely … referred to as a genomic marker or a genetic marker) is a DNA sequence, typically with a known location in a genome. …
Educational Resources
Southern blotting is a laboratory technique used to detect a specific DNA sequence in a blood or tissue sample.
… is a laboratory technique used to detect a specific DNA sequence in a blood or tissue sample. … Deoxyribonucleic Acid (DNA), Electrophoresis, Northern Blot, Probe, Restriction … blot analysis is a laboratory method used to study DNA. Specifically, purified DNA from a biological sample …
Fact Sheets
A knockout mouse is a laboratory mouse in which researchers have inactivated an existing gene by replacing it or disrupting it with an artificial piece of DNA.
… replacing it or disrupting it with an artificial piece of DNA. … Knocking out the activity of a gene provides valuable … researchers use one of two methods to insert artificial DNA into the chromosomes contained in the nuclei of ES cells. … this is done by introducing an artificial piece of DNA that shares identical, or homologous, sequence to the …
Media Availability
Researchers have created a promising new method to accurately and more comprehensively analyze and interpret DNA sequence information from cancer patients.
… in some cases, more comprehensively analyze and interpret DNA sequence information from cancer patients. They have … different tumor sample storage methods produced comparable DNA sequencing information - an important step that may … accurately and more comprehensively analyze and interpret DNA sequence information from cancer patients. … Cancer DNA …
Educational Resources
Transgenic means that one or more DNA sequences from another species have been introduced by artificial means.
… Transgenic … Transgenic means that one or more DNA sequences from another species have been introduced by … artificial means. … Cell, Cloning, Deoxyribonucleic Acid (DNA), Gene, Germ Line … Transgenic refers to an organism or … been altered by the introduction of one or more foreign DNA sequences from another species by artificial means. …
News Release
NIH researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer.
… researchers have identified a striking signature in tumor DNA that occurs in five different types of cancer. They also … specific signature results from a chemical modification of DNA called methylation, which can control the expression of … genes like a dimmer on a light switch. … Higher amounts of DNA methylation (hypermethylation), like that found by the …