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Fact Sheets
Polymerase chain reaction (PCR) is a technique used to "amplify" small segments of DNA.
… (PCR) is a technique used to "amplify" small segments of DNA. … Sometimes called "molecular photocopying," the … technique used to "amplify" - copy - small segments of DNA. Because significant amounts of a sample of DNA are necessary for molecular and genetic analyses, studies …
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Ribonucleic acid (RNA) is a molecule similar to DNA. Unlike DNA, RNA is single-stranded.
… (RNA) … Ribonucleic acid (RNA) is a molecule similar to DNA. Unlike DNA, RNA is single-stranded. … Cell, Genetic Code, Deoxyribonucleic Acid (DNA), Protein, Uracil, Adenine, Cytosine, Guanine, Messenger …
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A cytogeneticist is a geneticist who specializes in the study of chromosomes and the structure and function of the cell.
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A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli).
… … A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). … Cloning, Bacteria, Bioengineering, DNA Sequencing, Base Pair, Chromosomes … A bacterial …
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Antisense is the non-coding DNA strand of a gene.
… Antisense … Antisense is the non-coding DNA strand of a gene. … Non-coding DNA, Messenger RNA, Protein Synthesis … Antisense is the non-coding DNA strand of a gene. In a cell, antisense DNA serves as the …
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A base pair consists of two complementary DNA nucleotide bases that pair together to form a “rung of the DNA ladder.”
… Base Pair … A base pair consists of two complementary DNA nucleotide bases that pair together to form a “rung of the DNA ladder.” … Genetic Code, Nucleotides, Amino Acids, … Cytosine, Guanine, Thymine, Base Pairs, Double Helix, DNA … A base pair consists of two complementary DNA
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Shotgun sequencing is a laboratory technique for determining the DNA sequence of an organism's genome.
… sequencing is a laboratory technique for determining the DNA sequence of an organism's genome. … Deoxyribonucleic Acid (DNA), DNA Sequencing, Genome, Human Genome Project … Shotgun …
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A mutagen is a chemical or physical phenomenon, such as ionizing radiation, that promotes errors in DNA replication.
… such as ionizing radiation, that promotes errors in DNA replication. … Mutagen, DNA Mutation, DNA Replication, Cancer … A mutagen is a chemical or physical …
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Chromatin is a substance within a chromosome consisting of DNA and protein.
… Chromatin is a substance within a chromosome consisting of DNA and protein. … Chromosome, Histones, Gene Expression, DNA … Chromatin refers to a mixture of DNA and proteins that form the chromosomes found in the cells …
Staff
Dr. Paul Liu is a senior investigator in NHGRI's Translational and Functional Genomics Branch. ​
… (CBFb and RUNX1, respectively) that form a dimer for DNA binding and gene expression regulation, are frequent … Current and future efforts in Dr. Liu's lab include more functional studies of CBFβ-SMMHC with novel transgenic mouse … in the zebrafish, this finding demonstrated significant functional conservation between mammalian and zebrafish …