Search Results
Facet (Page)
Refine Your Search
Audiences
Content Formats
Events
Sections
Divisions
News Release
NHGRI researchers, collaborators at the University of California (UC) San Diego, UC Davis and the University of Pittsburgh School of Medicine lay out a new framework for comparing dog-to-human aging, one that uses epigenetics as a biological marker to better understand the aging process.
… between humans and domestic dogs provides an emerging model of aging. … One of the most common misconceptions is … the results obtained with humans. Dogs are a useful model for such comparisons because much of their environment, …
News Release
The zebrafish is a powerhouse tool that helps researchers better understand the genes that are implicated in disease.
… National Institutes of Health live nearly half a million organisms that breathe underwater, develop from an egg so … researchers, the reasons for using zebrafish as their model organism of choice are as varied as the diseases they … For Dr. Brooks' research program, using the zebrafish as a model is both practical and eye-opening."The zebrafish …
Research at NHGRI
The Technology Transfer Office is responsible for transferring NHGRI technologies to the private sector and exchanging research materials with outside groups.
News Release
A genetic mutation that triggers bladder cancer in dogs is identical to a mutation that is implicated in multiple human cancers.
… way that canines may come to our aid-as a powerful animal model for research into human cancer. … A genetic mutation … cancers are similar, and dogs already have served as a model in cancer research. They were central to immune system … Occurring Canine Bladder Cancer-Evidence for a Relevant Model System and Urine-based Diagnostic Test , Molecular …
Fact Sheets
Comparative genomics is a field of biological research in which researchers compare the complete genome sequences of different species.
… By carefully comparing characteristics that define various organisms, researchers can pinpoint regions of similarity and … Human Genome Project sequenced the genomes of a number of model organisms that are commonly used as surrogates in … as ENCODE (Encyclopedia of DNA Elements) and modENCODE (model organism Encyclopedia of DNA Elements) have compared …
News Release
Scientists are using an exciting gene editing tool called CRISPR/Cas9 to protect plants from harmful DNA viruses, strengthening the plant's protections.
… system has previously been adapted for use in many organisms, and this latest iteration develops gene-editing … economic losses. After looking at the machinery of simple organisms like bacteria, scientists set out to answer whether … species was chosen because it is well understood as a model organism, and new findings can be easily applied to …
Fact Sheets
Deoxyribonucleic acid (DNA) is a molecule that contains the biological instructions that make each species unique.
… with the instructions it contains, is passed from adult organisms to their offspring during reproduction. … In organisms called eukaryotes, DNA is found inside a special … the nucleus. Because the cell is very small, and because organisms have many DNA molecules per cell, each DNA molecule …
News Release
NIH researchers identified a novel role for a gene known as heat shock protein 60, finding it is critical in tissue regeneration and wound healing.
… dramatically accelerates wound closure in a diabetic mouse model. … The study also describes the mechanism by which this … that the molecule might also be involved in an organisms' ability to regenerate. Using zebrafish - an ideal model for this work because fish can regenerate many tissues, …
Fact Sheet
Viruses are bundles of genetic material wrapped in a protein coat that can infect living things.
… in viral transmission. … How do viruses infect living organisms?   Viruses have proteins on their surface that … particles that are halfway between living and nonliving organisms. They are so small (a millionth of a millimeter) …
News Release
Genome: Unlocking Life's Code exhibition is going on tour after having completed a 14-month engagement at the Smithsonian's National Museum of Natural History.
… to regulate life. Visitors will see a three-dimensional model of a human genome and watch interviews with Human …