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News Release
The newly launched Impact of Genomic Variation on Function (IGVF) consortium to include 30 U.S. sites.
… Genomic Variation on Function (IGVF) consortium, initiated and funded by NIH’s National Human Genome Research Institute … how genomic variation alters human genome function, and how such variation influences human health and disease.   … alternate orders of the As, Cs, Gs and Ts that make up our DNA — combined with the environment and lifestyle ultimately …
Educational Resources
A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli).
… … A bacterial artificial chromosome (BAC) is an engineered DNA molecule used to clone DNA sequences in bacterial cells (for example, E. coli). … … taken up by bacterial cells. As the bacterial cells grow and divide, they amplify the BAC DNA, which can then be …
Educational Resources
Antisense is the non-coding DNA strand of a gene.
… Antisense … Antisense is the non-coding DNA strand of a gene. … Non-coding DNA, Messenger RNA, Protein Synthesis … Antisense is the non-coding DNA strand of a gene. In a cell, antisense DNA serves as the …
News Release
This publication and the release of the accompanying data address knowledge gaps across genomics and are certain to have a continuing impact in the field.
… limited degree to which this variation has been sampled and evaluated. … A ground-breaking report published in Nature … of natural selection on genes related to viral immunity, DNA repair, and metabolism. This paper also makes an important …
Educational Resources
A base pair consists of two complementary DNA nucleotide bases that pair together to form a “rung of the DNA ladder.”
… Base Pair … A base pair consists of two complementary DNA nucleotide bases that pair together to form a “rung of the DNA ladder.” … Genetic Code, Nucleotides, Amino Acids, … has a backbone made of alternating sugar (deoxyribose) and phosphate groups. Attached to each sugar is one of four …
Educational Resources
Shotgun sequencing is a laboratory technique for determining the DNA sequence of an organism's genome.
… sequencing is a laboratory technique for determining the DNA sequence of an organism's genome. … Deoxyribonucleic Acid (DNA), DNA Sequencing, Genome, Human Genome Project … Shotgun …
Educational Resources
Chromatin is a substance within a chromosome consisting of DNA and protein.
… Chromatin is a substance within a chromosome consisting of DNA and protein. … Chromosome, Histones, Gene Expression, DNA … Chromatin refers to a mixture of DNA and proteins that …
Educational Resources
A mutagen is a chemical or physical phenomenon, such as ionizing radiation, that promotes errors in DNA replication.
… such as ionizing radiation, that promotes errors in DNA replication. … Mutagen, DNA Mutation, DNA Replication, Cancer … A mutagen is a … radioactive substances, x-rays, ultraviolet radiation and a wide variety of chemicals. Exposure to a mutagen can …
Educational Resources
A plasmid is a small, often circular DNA molecule found in bacteria and other cells.
… Plasmid … A plasmid is a small, often circular DNA molecule found in bacteria and other cells. … Bacteria, Chromosome, Deoxyribonucleic Acid (DNA), Gene, Cloning, DNA Sequencing, Genetic Engineering …
Educational Resources
Polymerase chain reaction (PCR) is a laboratory technique used to amplify DNA sequences.
… reaction (PCR) is a laboratory technique used to amplify DNA sequences. … Deoxyribonucleic Acid (DNA), DNA Replication, Enzyme, Genome, Primer … Polymerase … primers to select a segment of the genome to be amplified, and then multiple rounds of DNA synthesis to amplify that …