Search Results
Genetic Disorders
Gaucher disease is an autosomal recessive inherited disorder of metabolism where a type of fat (lipid) called glucocerebroside cannot be adequately degraded.
… frequently among individuals who are of Ashkenazi Jewish ancestry. Type 1 Gaucher disease is present 1 in 500 to 1 in 1000 people of Ashkenazi Jewish ancestry, and approximately 1 in 14 Ashkenazi Jews is a …
The Genomics Landscape
In the March 3, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., highlights the new fact sheets produced by the institute's Communications and Public Liaison Branch.
… guidance on the use of race, ethnicity, and genetic ancestry in genomics research. The NASEM study is sponsored …
15 Ways Genomics Influences Our World
Genomics is fostering an appreciation for what our DNA means for our health, identities and culture.
… they might be abused. … The broad availability of genomic ancestry testing is influencing the way we think about the concept of race in America (see Human Origins  and Ancestry ). We now understand that skin color, as one … intertwined relationships between a person's or groups' ancestry, ethnicity, and racial identity. The National Human …
Profile
Dr. Hanchard talks about his journey into genetics research, his collaborations with international researchers, and the importance of determination in science.
… Hanchard studies are more common in individuals of African ancestry. In fact, diversity is at the core of his research … potential to improve the healthcare of those with African ancestry, but also helps researchers understand how the human …
Event
The Inter-Society Coordinating Committee for Practitioner Education in Genomics (ISCC-PEG) will hold its 11th annual meeting online on February 16, 2022.
… L, Wilbur WJ, Lu Z, Brody LC, Bonham VL. Evolving use of ancestry, ethnicity, and race in genetics research-A survey …
Staff
Dr. Elisabeth F. Heuston is a molecular biology and bioinformatics Staff Scientist with the Center for Research on Genomics and Global Health (CRGGH).
… of complex traits among populations of African ancestry. Using her multidisciplinary background, she aims to …
News Release
Genomicists and clinicians are beginning to offer patients genetic testing for a list of treatable diseases apart from the one that brought them into the clinic.
… she thought it would be a fun way for him to find out his ancestry. Her father took the test, and his results revealed a high percentage of Jewish ancestry. Surprised by these results, Morris also decided to take an ancestry test, which verified that she was a quarter Jewish. …
Research at NHGRI
A list of publications led by or in collaboration with the Center for Research on Genomics and Global Health.
… polygenic prediction for kidney function in persons with ancestry from Africa and the Americas. Cell Genom . … C, AMP-T2D-GENES Consortium, Li Y, Hanover JA, Simonds WF. Ancestry-specific high-risk gene variant profiling unmasks … TO, Adeyemo A , Rotimi C . Genes, environment, and African ancestry in cardiometabolic disorders. Trends Endocrinol …
News Release
A team from the NIH has surmounted a major obstacle to testing potential drug therapies for a rare, genetic condition called Gaucher disease.
… people, but is more common in people of Ashkenazi Jewish ancestry. There are three types of the disease: Type 1 causes …
Research at NHGRI
NHGRI center focused on computationally intensive approaches to analyze large-scale genomic data and identifying genetic contributions to human disease.
… biomolecular processes, animal development, fertility, ancestry, infectious disease, agriculture, bioconservation, …