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- Ethical, Legal and Social Implications (ELSI) Research Program6
- Genomics-Enabled Learning Health Systems (gLHS)2
- Genetic Architecture of Complex Traits1
- Genome Technology Program5
- Human Genome Reference Program (HGRP)2
- Impact of Genomic Variation on Function (IGVF) Consortium3
- Encyclopedia of DNA Elements (ENCODE) Project1
- Molecular Phenotypes of Null Alleles in Cells (MorPhiC)1
- Genomic Innovator Awards2
- NHGRI Genomic Data Science Analysis, Visualization and Informatics Lab-space (AnVIL)3
- Genomics Research to Elucidate the Genetics of Rare Diseases (GREGOR) Consortium2
- Developmental Genotype-Tissue Expression (dGTEx)1
- Multi-Omics for Health and Disease (Multi-Omics)1
News Release
Researchers find weaker immune response to viral infections in children with mitochondrial disorders
NIH researchers analyzed the gene activities of immune cells in children with mitochondrial disorders and found that their B cells, which produce antibodies to fight viral infections, are less able to survive cellular stress.
… of Health (NIH) researchers found that altered B cell function in children with mitochondrial disorders led to … in Immunology was led by researchers at the National Human Genome Research Institute (NHGRI), who analyzed gene activity … Mitochondria are important components of nearly every cell in the body because they convert food and oxygen into …
Educational Resources
Centrioles are paired barrel-shaped organelles located in the cytoplasm of animal cells near the nuclear envelope.
… the cytoplasm of animal cells near the nuclear envelope. … Cell Biology, Organelles, Nucleus … Centrioles are paired … play a role in organizing microtubules that serve as the cell's skeletal system. They help determine the locations of the nucleus and other organelles within the cell. … Centrioles are paired barrel-shaped organelles …
Educational Resources
Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move.
… … Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move. … Cell Biology, Proteins, Nucleus … Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move. …
Genomics and Medicine
The NHGRI Genomic Medicine Working Group has compiled a list of interesting advances.
Educational Resources
Mitosis is a cellular process that replicates chromosomes and produces two identical nuclei in preparation for cell division.
… and produces two identical nuclei in preparation for cell division. … Mitosis, Meiosis, Cell Biology, DNA, Chromosome … Mitosis is the process by which a cell replicates its chromosomes and then segregates them, …
Educational Resources
Cytoplasm is the gelatinous liquid that fills the inside of a cell. It is composed of water, salts, and various organic molecules.
… is the gelatinous liquid that fills the inside of a cell. It is composed of water, salts, and various organic molecules. … Organelles, Mitochondria, Nucleus, Cell Biology … Cytoplasm is the gelatinous liquid that fills the inside of a cell. It is composed of water, salts, and various organic …
Educational Resources
Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move.
… … Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move. … Endoplasmic Reticulum, Proteins, Ribosomes, Cell Biology … Endoplasmic reticulum is a network of membranes inside a cell through which proteins and other molecules move. …
News Release
NHGRI researchers have identified a genomic signature for some aggressive prostate tumors, which may help healthcare providers pinpoint treatment options.
… challenge health care providers face in treating prostate cancer is distinguishing the aggressive, potentially … aggressive tumors. … Researchers with the National Human Genome Research Institute (NHGRI) and their collaborators … way to identify a specific subgroup of prostate cancer tumors with a known treatment option," said Elaine …
News Release
NHGRI researchers have developed the Families Sharing Health Assessment and Risk Evaluation (SHARE) workbook, which helps people use their family history to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer.
… with family members. … Researchers at the National Human Genome Research Institute (NHGRI), part of the National … to assess their risk for heart disease, diabetes, breast cancer and colorectal cancer. Since 2012, Laura Koehly, Ph.D., and her research …
Health FAQ
Discuss these questions with your doctor or health care provider.
… Education Project welcomes your feedback about the sickle cell disease gene therapy resources. Please email your … consent process. … Gene therapy can increase your risk of cancer. This risk could come from either the chemotherapy … an off-target effect and influence the activity of nearby cancer-causing genes, which could lead to the development of …