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Dr. Paul Liu is a senior investigator in NHGRI's Translational and Functional Genomics Branch.
… (CBFb and RUNX1, respectively) that form a dimer for DNA binding and gene expression regulation, are frequent … Current and future efforts in Dr. Liu's lab include more functional studies of CBFβ-SMMHC with novel transgenic mouse … in the zebrafish, this finding demonstrated significant functional conservation between mammalian and zebrafish …
Event
NHGRI workshop seeking scientific perspectives for relating genomic variation to human phenotype.
… NHGRI Staff 8:15 - 9:00 a.m. Current State of the Art: Functional Data, Analysis and Interpretation Hugo Bellen Lea … capabilities do we need to generate and make use of functional data? What is needed to overcome barriers to … and characterization of all genes and regulatory elements Co-Chairs: Kelly Frazer Wendy Chung Breakout 5 ( …
Educational Resources
Polymerase chain reaction (PCR) is a laboratory technique used to amplify DNA sequences.
… reaction (PCR) is a laboratory technique used to amplify DNA sequences. … Deoxyribonucleic Acid (DNA), DNA Replication, Enzyme, Genome, Primer … Polymerase chain …
The Genomics Landscape
In the July 2021 issue of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., reflects on the legacy the LINCS program leaves as it has completed its goal of creating a large-scale, systematically generated molecular and cellular dataset.
Educational Resources
A genetic marker is a DNA sequence with a known physical location on a chromosome.
… Genetic Marker … A genetic marker is a DNA sequence with a known physical location on a chromosome. … Genetic Marker, DNA Sequence, Chromosome, Genetic Disease, Inheritance … A genetic marker is a DNA sequence with a known physical location on a chromosome. …
Educational Resources
Double helix is the description of the structure of a DNA molecule.
… … Double helix is the description of the structure of a DNA molecule. … Adenine, Cytosine, Guanine, Thymine, ACGT, Base Pairs, DNA, Watson And Crick … Double helix, as related to genomics, … is a term used to describe the physical structure of DNA. A DNA molecule is made up of two linked strands that …
Educational Resources
Cloning is the process of making identical copies of an organism, cell, or DNA sequence.
… of making identical copies of an organism, cell, or DNA sequence. … DNA Sequence, Ethics, Cloning … Cloning, as it relates to … or virtually identical, copies of an organism, cell or DNA sequence. The phrase “molecular cloning” typically refers …
Educational Resources
Genetic engineering is the process of using recombinant DNA (rDNA) technology to alter the genetic makeup of an organism.
… … Genetic engineering is the process of using recombinant DNA (rDNA) technology to alter the genetic makeup of an organism. … Genetic Engineering, Recombinant DNA, Genes, DNA Sequence … Genetic engineering (also called genetic …
Educational Resources
A restriction enzyme is an enzyme isolated from bacteria that cuts DNA molecules at specific sequences.
… enzyme is an enzyme isolated from bacteria that cuts DNA molecules at specific sequences. … Bacteria, Deoxyribonucleic Acid (DNA), Enzyme, Genetic Engineering, Recombinant DNA (rDNA) … A restriction enzyme is a protein isolated from …
Educational Resources
A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during cell division, exposure to ionizing radiation, exposure to chemicals called mutagens, or infection by viruses.
… Mutation … A mutation is a change in a DNA sequence. Mutations can result from DNA copying mistakes made during cell division, exposure to … called mutagens, or infection by viruses. … Mutation, DNA Sequence, Germ Line, Gene … A mutation is a change in the …