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Fact Sheet
Ribonucleic acid (RNA) is an essential molecule that performs many roles in the cell, from carrying the instructions to make proteins to regulating genes.
… RNA are very similar molecules, and just like all living organisms have DNA, all living organisms have RNA as well. There are many different types … functions. Some types of RNAs are only found in certain organisms. The functions of RNA are broad and include …
News Release
NIH researchers have identified a gene that makes yeast resistant to a lethal toxin.
… mechanisms underlying resistance to toxins in simple organisms, such as yeast. A particularly important way that organisms vary is in how much they’re affected by toxins. … Research Institute (NHGRI), part of NIH, used yeast as a model organism. While researchers have long known about …
Research Funding
NHGRI is initiating a new program-the Impact of Genomic Variation on Function (IGVF) Consortium to develop a framework for systematically understanding the effects of genomic variation on genome function and how these effects shape phenotypes.
Profile
Dr. Pavan looks back on his career at NHGRI, highlights pivotal moments and shares his future plans in artistic woodworking and community mediation.
… gene from a screen or from observing a trait in an animal model, and then we explored what that gene did. That would …
FAQ
Frequently asked questions from the September 23, 2024 pre-application webinar the NHGRI ELSI Program hosted.
The Genomics Landscape
In the June 2024 issue of The Genomics Landscape, NHGRI Director Eric Green recognizes the 2023 recipients of the Bettie J. Graham Leadership Award for Enhancing DEIA in the Genomics Workforce.
… NHGRI has also recently released a foldable paper model of tRNA , which provides a fun way to explore RNA … which ones might affect misfolding outcomes. The resulting model can be adapted for other proteins, and understanding …
The Genomics Landscape
In the December 8, 2022 edition of The Genomics Landscape, NHGRI Director, Eric Green, M.D., Ph.D., looks back on the success of the Genome: Unlocking Life's Code exhibition as it came to a close in November.
… milestone in that mouse is a widely used animal model for many human diseases. In NIH news, Lawrence Tabak, …
FAQ
Questions and answers to help applicants responding to the ML/AI Tools to Advance Genomic Translational Research (MAGen) notice of funding opportunities (NOFOs): RFA-HG-24-004 and RFA-HG-24-005.
… validation. What is meant by “Guiding the Common Data Model Development”? The Common Data Model is a standard and extensible collection of schemas … semantics, to facilitate data interoperability. This model should allow for seamless deployment, training, and …
Fact Sheets
Cloning describes a number of different processes that can be used to produce genetically identical copies of a biological entity.
… materials, including genes, cells, tissues and even entire organisms, such as a sheep. … Yes. In nature, some plants and single-celled organisms, such as bacteria , produce genetically identical …
News Release
NIH researchers have sequenced the whole genome of a dog native to Sardinia, Italy, and discovered in it clues about the migration of humans to the area.
… pressures are any natural or man-made forces that cause organisms to favor certain observable characteristics …