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News Release
Researchers identified regions of the genome associated with skin color variation in some African populations, furthering skin disease and cancer research.
… opening new avenues for research on skin diseases and cancer in all populations. … These findings may help researchers determine if humans with certain DNA sequences are more or less susceptible to DNA damage … sequenced blood DNA and analyzed it to determine the DNA variations - called alleles -- that were responsible for the …
Genetic Disorders
Skin cancer is the most common type of cancer in the United States.
… Skin cancer is the most common type of cancer in the United … a new growth or a sore that doesn't heal. Both basal and squamous cell cancers are found mainly on areas of the … booths, also play a role. UV radiation can damage the DNA, or genetic information, in skin cells, creating …
15 Ways Genomics Influences Our World
​Genomics is helping us understand what makes each of us different and what makes us the same.
… is helping us understand what makes each of us different and what makes us the same. … Did you know that at the … each other in all sorts of ways. Those differences in your DNA help to determine what you look like and what your risk … only the DNA in blood is typically sequenced, mosaic-like variations elsewhere in the body could be missed. Single-cell …
News Release
The skin microbiota plays an intricate role in the human immune system, directing many immune functions and defending against bacterial pathogens.
… Bruce Agnew … The billions of microbes that reside on human skin - probably more than 10 billion microbial cells on each … immune system, actually directing many immune functions and helping to defend its host against invading bacterial … of the National Human Genome Research Institute (NHGRI), and Yasmine Belkaid, Ph.D., head of the Mucosal Immunology …
Media Availability
Researchers find that more than 80 percent of mouse genes had variations in the nearby regulatory DNA that affects gene activity.
… … Media Availability Complex traits such as height and susceptibility to common diseases like diabetes and heart … While changes in many genes themselves play a role, small variations in DNA sequences near genes that control when and how much a …
Educational Resources
Genomic variation refers to diversity in gene frequencies.
… Family Health History … Genomic variation refers to DNA sequence differences among individuals or populations. …
News Release
Researchers have now identified and catalogued more species - nearly 200 new bacteria and thousands of viruses - that reside on the human skin than has ever been possible, largely due to advances in bioinformatics and laboratory techniques.
… Rachael Zisk … Study identifies nearly 200 new bacteria and thousands of viruses residing on skin, far more than previously known. … Researchers have now … a technique that randomly samples many short sequences of DNA. In this case, the researchers used skin samples that …
Educational Resources
A copy number variation (CNV) is when the number of copies of a particular gene varies from one individual to the next.
… from one individual to the next. … Chromosomes, Disease, DNA, Gene Variation … Copy number variation (abbreviated CNV) … in which the number of copies of a specific segment of DNA varies among different individuals’ genomes. The … about through duplications, deletions or other changes and can affect long stretches of DNA. Such regions may or may …
Research Funding
The Genomic Variation Program supports large-scale studies of human genetic variation.
… About 99.5 percent of a person's DNA is the same as any unrelated person's DNA. Differences in … explains some of the differences among people, such as eye color and blood group, as well as whether a person has a higher or …
Fact Sheet
Genomic variation accounts for some of the differences among people, including important aspects of their health and susceptibility to diseases.
…  Genomic variation reflects the differences in a person’s DNA compared to other peoples’ DNA.  There are multiple … subset of genomic variants contributes to human health and disease.  Researchers create reference human genome … variants influence physical characteristics, like eye color and height; others influence health conditions or how a …