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News Release
NIH researchers identified a novel role for a gene known as heat shock protein 60, finding it is critical in tissue regeneration and wound healing.
… shock protein 60 ( Hsp60 ), finding that it is critical in tissue regeneration and wound healing. The study found that topical … we injected Hsp60 directly to the site of injury, the tissue surrounding the wound started to regenerate faster," …
Jobs at NHGRI
Funded postdoctoral positions are available in the laboratory of Dr. Shawn Burgess, within NHGRI's Translational and Functional Genomics Branch.
… Burgess lab is on the genetics and functional genomics of tissue regeneration and wound healing with an emphasis on hearing … … Qualifications … How to Apply … Functional Genomics of Tissue Regeneration … Funded postdoctoral positions are …
News Release
Grants are awarded to GTEx project to explore human gene expression and regulation in different tissues, and how genomic variation modulates that expression.
… of Health has awarded eight grants as part of the Genotype-Tissue Expression (GTEx) project to explore how human genes … The GTEx awards will contribute to a resource database and tissue bank that researchers can use to study how inherited … lead to disease. The grants will add data from analyses of tissue samples whose collection began in 2010, as well as …
Research Funding
The developmental Genotype-Tissue Expression initiative's goal is to catalog and analyze transcriptional profiles from a wide variety of tissues from the pediatric period, including neonates through adolescents, in a post-mortem setting.
… Philadelphia, PA University of Maryland Brain and Tissue Bank Baltimore, MD University of Rochester Medical … Yale University New Haven, CT … The Developmental Genotype-Tissue Expression (dGTEx) project, co-funded by the National … a molecular and data analysis resource as well as a tissue bank to study the regulation of gene expression in …
Research Funding
The Genotype-Tissue Expression (GTEx) Project will create a resource that researchers can use to study how inherited changes in genes lead to common diseases
… (NIH) in September 2010 (See: NIH launches Genotype-Tissue Expression project ), GTEx will create a resource that … to common diseases. It will establish a database and a tissue bank that can be used by many researchers around the … studying many different diseases. The gift of your tissue or your loved one's tissue may lead to research which …
News Release
NIH will award $38.5 million over five years to the Developmental Genotype-Tissue Expression (dGTEx) project, which aims to build a widely available resource of human developmental gene expression in a multitude of tissues for use in basic and clinical research.
… Health (NIH) saw a gap in the availability of high-quality tissue samples and information on gene expression — important … In response to this realization, they began the Genotype-Tissue Expression (GTEx) consortium, which successfully obtained high-quality tissue samples from over 900 adult postmortem donors. It also …
Genetic Disorders
Marfan syndrome an inherited disorder of connective tissue occurring once in every 10,000 to 20,000 individuals.
… Marfan syndrome an inherited disorder of connective tissue occurring once in every 10,000 to 20,000 individuals. … one of the most common inherited disorders of connective tissue. It is an autosomal dominant condition occurring once … the most notable occurring in eye, skeleton, connective tissue and cardiovascular systems. Marfan syndrome is caused …
Event
NHGRI, NICHD, NIMH, and ORIP program staff held a pre-application webinar with an interactive Q&A session for the Non-Human Primate Developmental Genotype-Tissue Expression (NHP dGTEx) Project.
… RFH-HG-21-026 - Non-Human Primate Developmental Genotype-Tissue Expression (NHP dGTEx) Project (U24 Clinical Trials … within this project. Either way works. Will use of banked tissue hurt any proposal because of potential quality control … webinar for the Non-Human Primate Developmental Genotype-Tissue Expression Project funding opportunities and answer …
News Release
National Institutes of Health researchers have discovered a specific network of proteins that is necessary to restore hearing in zebrafish through cell regeneration. The study may inform the development of treatments for hearing loss in humans.
… the role of transcription factors in facilitating cell regeneration … Brightfield image of a two-day-old zebrafish … for researchers to understand the biology of cell regeneration in zebrafish before translating the findings to … recover hearing after injury,” said Burgess. “How and why regeneration happens in these animals remain a mystery that …
Educational Resources
A fibroblast is the most common type of cell found in connective tissue.
… is the most common type of cell found in connective tissue. … Cell Biology, Wound Healing … A fibroblast is a … of cell that contributes to the formation of connective tissue, a fibrous cellular material that supports and … is the most common type of cell found in connective tissue. … Educational Resources …